Indomethacin treatment of infantile cortical periostosis
(3-5) In its complete form, PDP is characterized by pachyderma (thickening of the facial skin), skeletal changes (periostosis
), excessive sweating (hyperhidrosis), and acropachia (digital clubbing).
All available remains also were evaluated morphologically for signs of systemic infection (e.g., periostosis
, osteomyelitis, lytic lesions) or other pathological conditions that may present confounding variables (e.g., DISH, ankylosing spondylitis, trauma).
Clinical presentation is classified into the complete form (pachydermia, clubbing, and periostosis
), the fruste form (prominent pachydermia with minimal skeletal changes), and an incomplete form which has no pachydermia (4).
INTRODUCTION: Pachydermoperiostosis (PDP) is a primary hypertrophic osteoarthropathy, characterized by various clinical expressions with the involvement of digital clubbing, pachydermia, seborrhoea, periostosis
and arthritis or arthralgia.
The disease is characterized by hypertrophic skin changes, clubbing of fingers, and periostosis
. Dermatological findings are relatively severe and involve face, skull, skin, palms, and soles.
Pachydermoperiostosis (idiopathic clubbing and periostosis
) (and genetic and physiologic considerations).
The presence of long clubbed fingers and hypertrophic periostosis
are other common NNS features.
The presence of clubbing and radiographic evidence of periostosis
of the tubular bones without underlying diseases correctly diagnosed PDP in this patient.
* Osteopatia hipertrofica: acropaquias, sinivitis, periostosis
INTRODUCTION: Pachydermoperiostosis (PDP), the primary or idiopathic form of hypertrophic osteoarthropathy (HOA), is characterized by pachydermia, clubbing of digits of both hands and feet, and periostosis
. It is a rare genetic disorder with autosomal dominant transmission with variable penetrance or autosomal recessive transmission.
It is characterized by digital clubbing, pachydermia (thickening of the facial skin and/or scalp), and periostosis
(swelling of periarticular tissue and subperiosteal new bone formation).