periosteal osteosarcoma


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Related to periosteal osteosarcoma: parosteal osteosarcoma

per·i·os·te·al os·te·o·sar·co·ma

chondroblastic osteosarcoma occurring on the surface of bones without involvement of the marrow; usually presents in adolescents and young adults as a lucent defect with bone spicules extending into soft tissues. Histologically, the tumor is intermediate to high grade, and the cartilage is lobulated.
Farlex Partner Medical Dictionary © Farlex 2012

periosteal osteosarcoma

An uncommon (less than 2%) osteosarcoma (OS) with the same demographic as conventional OS. It is related to periosteal chondrosarcoma, and usually arises in diaphysis of the proximal tibia or distal femur.

Imaging
Small radiolucencies on bone surface with bone spicules perpendicular to shaft and penetrating soft tissues; no medullary involvement.

DiffDx
Parosteal chondrosarcoma—lobules of malignant cartilage with calcification and surface endochondral ossification, no malignant osteoid.

Genetics
Usually diploid.

Prognosis
Intermediate between high-grade and parosteal (juxtacortical) OSs or chondrosarcoma; high local recurrence; 15% metastasise.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
The silence of the literature regarding the efficacy of chemotherapy on periosteal osteosarcoma will lead clinicians to draw on their experience of other subtypes of osteosarcoma, in particular that of high-grade conventional osteosarcoma, to make treatment recommendations.
Sim, "Periosteal osteosarcoma: long-term outcome and risk of late recurrence," Clinical Orthopaedics and Related Research, vol.
Campanacci, "Periosteal chondrosarcoma and periosteal osteosarcoma: two distinct entities," Journal of Bone and Joint Surgery, vol.
Giunti, "Periosteal osteosarcoma. Review of 41 cases, 22 with long-term follow-up," Italian Journal of Orthopaedics and Traumatology, vol.
Eckardt, "Periosteal osteosarcoma," Clinical Orthopaedics and Related Research, vol.
Gannon, "Imaging of periosteal osteosarcoma: radiologic-pathologic comparison," Radiology, vol.