perinuclear


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per·i·nu·cle·ar

(per'i-nū'klē-ăr),
Surrounding a nucleus.
Synonym(s): circumnuclear

perinuclear

/peri·nu·cle·ar/ (-noo´kle-ar) near or around a nucleus.

perinuclear

(pĕr″ĭ-nū′klē-ăr) [″ + L. nucleus, a kernel]
Around a nucleus.
References in periodicals archive ?
Arsenic trioxide stabilizes accumulations of adeno-associated virus virions at the perinuclear region, increasing transduction in vitro and in vivo.
Perinuclear clearing was a striking finding in most of the cells on smears and cell block (Figures 1b and 2b).
Thus, the research results show that within the adaptive processes taking place in the hens' nuclear red cells a particular role is assigned to the capacity of the perinuclear space which decreased significantly, apparently, such reduction is aimed at increase of the cell effective volume.
ANCAs come in two types: cytoplasmic (cANCA), which are antibodies directed against proteinase 3, and perinuclear (pANCA), directed most often against myeloperoxidase.
Autoantigens defined by experimental serum and B-cell analysis in RA syndromes in animals and humans (10) Type/nature Specificity Autoantigen Citrulline-containing peptide Keratin Perinuclear factor Savoy antigen Filaggrin Human leukocyte antigen Calpastatin Immunoglobulin (rheumatoid factor) Calreticulin Antineutrophil cytoplasmic antigen Antinuclear antibody Immunoglobulin heavy-chain protein / p68 Heteronuclear ribonucleoprotein A2 (RA33) Glucose-6-phosphate isomerase Cartilage (organ Collagen type II specific) Chondrocyte antigen 65 Large aggregating chondroitin sulfate proteoglycan (aggrecan) Human chondrocyte glycoprotein 39 Cartilage oligomeric matrix protein Non-autoantigens Bacterial heat shock protein
Perinuclear staining ANCA (p-ANCA) directed against myeloperoxidase (MPO-ANCA) was positive, but cytoplasmic staining ANCA (c-ANCA) against proteinase-3 (PR-3) was negative.
Cbfa 1 appeared in a diffuse form around the perinuclear region.
The cytoplasmic ANCA pattern is typically associated with antibodies to proteinase 3 (PR3), whereas the perinuclear ANCA pattern is typically associated with antibodies to myeloperoxidase (MPO).
ARL that take on a plasmacytoid appearance contain lymphoma cells with moderate amounts of basophilic cytoplasm, have eccentric nucleolated nuclei, and occasionally an identifiable perinuclear hof.
Within 4 h post infection, large number of cells displayed intense perinuclear chromatin aggregation, which is characteristic of cells undergoing apoptosis (Fig.
The positive signals in the nucleus in all examined tissues were particularly intense in the perinuclear membrane and nucleolus.