On examination, the patient was found to have multiple eruptions including 1-4 cm tense bulla (blisters) filled with serous and hemorrhagic fluid, superficial erythematous erosions, 0.2-2 cm targetoid macules and papules with perilesional
vesicles, and some coalescing in a herpetiform distribution.
Although it has been suggested that ipsilesional, and even perilesional
, tissue is best suited to support recovery, there are several factors that influence recruitment of undamaged tissue during functional recovery, including poststroke alterations in vascular physiology.
The purpose of this study was to investigate the usefulness of the Melan-A marker for identifying and estimating melanocyte content in different zones of non-segmental vitiligo lesions: the zone of depigmented skin, marginal zone (bordering the area), and zone of perilesional
normally pigmented skin.
In addition, it has been found that mitochondria appeared swollen and lack a normal and organized ultrastructure of internal and external membrane systems in keratinocytes from perilesional
skin of vitiligo patients and the number of Langerhans cells increased in varying differentiative phases, in lesional skin of vitiligo patients, indicating that mitochondrial damage is associated with the increase in ROS production and, hence, oxidative stress decreased total antioxidant capacity .
vasogenic oedema was seen in all except the basal ganglia lesion.
Enhancement may be lesional or perilesional
. Additionally, small lesions (less than 1.5cm) tend to uniformly enhance while larger lesions (greater than 1.5cm) most commonly demonstrate transient rim enhancement (i.e.
skin biopsy was negative for direct immunofluorescence.
All of them were solitary with no perilesional
edema or contrast enhancement.
For the measurement of the outcome indicators of tissue integrity: skin and mucous membranes, propaedeutic methods of inspection and palpation were used, however two of the indicators were measured by specific instruments: temperature by means of a Minipa[R] brand MT-305 infrared thermometer, calibrated with emissivity of 0.98, specific to human skin measured by an infrared wave coming through at a distance of 10 cm from the lesion; and tactile sensitivity of the perilesional
area and dorsum of the foot, through the Semmes-Weinstein monofilaments or the Sorry[R] brand, securing the cord of the apparatus so that the filament is perpendicular to the skin surface of the patient and the pressure taken must achieve a sufficient force to bend the filament.
The aim of the study was to evaluate the expression of these markers of mast cells in skin lesions and the perilesional
area, as well as in the serum of patients with DH and BP.
At the moment of the diagnosis CT scan revealed a bulky mass (8 x 7 cm) in the sigmoid colon with no cleavage plane with the bladder and the abdominal wall and perilesional
Direct immunofluorescence of perilesional
mucosa reveals linear deposits of IgG and complement in the subepidermal basement membrane zone.