Majocchi's granuloma (also known as nodular granulomatous perifolliculitis
) is a rare condition in which a dermatophyte invades the deeper layers of the dermis and subcutaneous tissue.
Familial perifolliculitis capitis abscedens et suffodiens in two brothers successfully treated with isotretinoin.
Successful treatment of perifolliculitis capitis abscedens et suffodiens with combined isotretinoin and dapsone.
Of 8 birds, Staphylococcus species was isolated from only 1 sample, a feather that was associated with mononuclear perifolliculitis
. All other feather pulp samples were negative for bacterial growth.
Acne-like eruption due to perifolliculitis
repeatedly appears on the upper body of BD patients and subcutaneous thrombophlebitis, so-called "thrombophlebitis migrans," is suddenly noticed on the lower extremities.
schoenleini 13 (34.2%) Similar species (isogenic) PCR 38 (65.5%) *3 (17.6%) * from other body sites *2 (18.2%) * from other infected family members * 8 (80%) * from closely contact animals 25 (65.2%) Different species (heterogenic) Skin 17 (29.3%) 12 (70.6%) Folliculitis biopsy * 3 (17.6%) * positive spores or hyphae 5 (29.4%) Perifolliculitis
Follow-up of the patients showed clinical improvement and mycological cure in 47.9% of patients after treatment with griseof-ulvin (500 mg/d), 80.8% after treatment with itraconazole (200 mg/d), and 70% after treatment with terbinafine (250 mg/d).
Observation of parasitic skin diseases demonstrated a high frequency of canine demodicosis, diagnosed by the presence of perifolliculitis
, mural folliculitis and follicle rupture, besides the presence of the parasite, in agreement with literature reports (1).
HS is characterized by perifolliculitis
which may destroy the pilosebaceous unit and in healing stages, by fibrosis6 and so was excluded in our case.
The histopathology of samples taken from the head and scalp reported occlusion folliculitis with mixed inflammatory infiltrate predominantly polymorphonuclear with destruction of the epidermal basal layer, stratum corneum spongiosis, exocytosis, and formation of intraepidermal abscesses; the inflammatory infiltrate compromised the follicular epithelium and the adjacent adnexal structures, findings compatible with acne conglobata and perifolliculitis
capitis abscedens et suffodiens (Figure 1).
A biopsy was taken of the occipital scalp lesion, and histopathology found that it was consistent with acute perifolliculitis
Compared with the baseline biopsy, the last biopsy showed a lower percentage of follicles with perifolliculitis