5,12) Low-grade PanIN or, rarely, highgrade PanIN, atrophy, periductal
fibrosis, squamous metaplasia, or acinar-ductal metaplasia have been seen in the adjacent pancreatic parenchyma.
Gynaecomastia is the result of different factors that induce a benign proliferation of the duct epithelium and also increased periductal
deposition of collagen.
Histopathologically, they are seen as firm, homogeneous masses characterized by marked fibrosis and lymphocytic infiltration, which are localized in periductal
, perivascular, and perilobar areas.
Clinically it may present with features similar to periductal
The presence of atypical lymphocytes in lymphoma, IgG4-positive plasma cells in IgG4-related Mikulicz's disease, periductal
and perivascular inflammation of lymphocytes and intralobular fibrosis in Sjogren's syndrome are the main factors that aid in the differential diagnosis of sarcoidosis.
Prenatal exposure to low doses of bisphenol A alters the periductal
stroma and glandular cell function in the rat ventral prostate.
PSCs are resident exocrine pancreas cells located in the periacinar, periductal
and perivascular spaces of the pancreas (Omary et al.
In mammary duct ectasia (MDE), the periductal
inflammation is the principal pathological expression.
The hepatic specimen revealed hyperplastic biliary epithelium cholestasis, periductal
fibrosis and edema in some portal areas accompanied by focal necrotic areas.
Viral replication in the salivary glands, including the ductal epithelium, can lead to periductal
interstitial edema and local inflammation, with infiltration of lymphocytes and macrophages.
The histological pattern of Sjogren's syndrome shows chronic periductal
inflammation of the salivary glands.
Microscopically, tumors to be composed of intracanalicular ductal growth pattern with marked proliferation of the stromal cells show periductal