Final pathology of the second excisional biopsy revealed IP, forid hyperplasia, and fibrocystic alternations (fibrosis, periductal
inflammation, apocrine metaplasia, macro-microcysts) (Figures 1-3).
The amyloid protein accumulates in perivascular, periductal
and intralobular areas in the breast.
It causes leakage of glandular secretion and accumulation of it in the periductal
area which causes an inflammatory reaction and result in a walled- off collection surrounded by granulation tissue and leads to formation of pseudo cyst.
(1995), found positive correlations between the age and incidence of orbital lobe atrophy and fibrosis in women and periductal
fibrosis in both men and women.
Sections of the adjacent liver showed variable bile duct proliferation, focal bridging and periductal
fibrosis, and cholestasis.
The results showed that the tumour was phyllodes, which are large, fast-growing masses that form from the periductal
stromal cells of the breast.
As the sweat is reabsorbed into the dermis or diffuses away from the periductal
area, SC will slowly recover, resulting in a rather flat SCR.
In histopathological examination, periductal
and perivascular lymphocytic infiltration and hyperplasia in the ductal epithelial cells were observed, and this was found consistent with grade 3 Chisholm (Figure 3).
In multidrug resistance-associated protein 2-deficient mice, a high level of hepatocyte necrosis and portal inflammation, a strong human cholangitis-like phenotype, and periductal
fibrosis have been observed (84).
It is hypothesized that the fluke itself resides in the bile ducts where it injures the lining and produces abnormalities such as advanced periductal
(a) There is dense lymphoplasmacytic infiltrate with acini atrophy and mild periductal
Moreover, microscopy showed several portal tracts with moderate periductal
fibrosis and inflammatory infiltrates dominated by lymphocytes and plasma cells and associated with eosinophilic granulocytes (in hot spots up to 13 /HPF).