Since our patient of histoid leprosy had an unusual episode of T2R reaction with fever, constitutional symptoms, bilateral pedal edema, perichondritis
, epididymo-orchitis and enlarged tender inguinal lymph nodes but without ENL, we believe this is the first published case report.
with the mononuclear cells and polymorphonuclear leukocytes at the fibrochondral junction (hematoxylin and eosin, (a) original magnification x50, (b) original magnification x200).
As mentioned previously, the key findings that should suggest a diagnosis of WG are a dense mixed inflammatory infiltrate (including lymphocytes, plasma cells, and eosinophils), microscopic foci of collagen necrosis (with or without histiocytic palisading), perichondritis
, capillaritis, hemosiderosis, and isolated osteoclast-like giant cells, the latter typically best seen at the edge of palisaded histiocytic reaction around necrosis.
One patient experienced an attack of perichondritis
involving the external ear 7 months postoperatively that was managed with conservative treatment; he subsequently developed an anteroinferior perforation that was treated surgically.
Among noninfectious cases, granulomatous perichondritis
of the nasal ala, sarcoidlike foreign body reaction from multiple piercing, paraphimosis from a distal penis pierce, and speech impairment, together with difficulty in chewing and swallowing from oral jewelry, have been reported (1,2,9,10).
In our study trauma was the most common factor in causation of pseudocyst of auricle, seen in 11 cases (34%), 3 cases (9%) had diabetes mellitus which if uncontrolled can lead to delayed fluid resorption and in worst scenario may even cause perichondritis
followed by destruction of auricular cartilage.
Since diabetes and perichondritis
are known to be associated, we recommend that for patients who present with recurrent episodes of perichondritis
, a basic metabolic panel and measurement of the glycosylated hemoglobin level be added to standard autoimmune laboratory testing to possibly identify undiagnosed diabetes.
4) Confluent ulceration progresses to deep stromal necrosis and perichondritis
after approximately 96 hours.
14) Local causes other than frostbite include trauma, inflammation, chondritis, and perichondritis
5) Proper management is aimed at restoring normal appearance of the ear, this can only be achieved if perichondritis
and re-accumulation of haematoma are avoided.
Auricular ossification has also been associated with inflammatory conditions such as chondritis, perichondritis
, and syphilitic perichondritis
, as well as with neoplasms such as nevi of the face, pilomatrixoma, and chondroid syringoma.
leading to sore throat in patients with active adult onset Still's disease.