pericentric inversion

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Related to pericentric inversion: isochromosome, reciprocal translocation

per·i·cen·tric in·ver·sion

inversion in a chromosome of a single segment that includes the centromere.
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Most of this karyotypic variation has been attributed to pericentric inversions and centric fusions, evidenced by comparative GTG- and CBG-banding, location of telomeres by in situ hybridization, and chromosome painting.
Analysis of 25 metaphase cells showed a pericentric inversion of one chromosome 21, with the breakpoint in the short arm at 21p12 and in the distal region of long arm at 21q22: 46, xx, inv (21) (p12; q22) in all cells (Fig.
The differences observed in the cytotype C2 in relation to the cytotype C1 (loss of one element of the metacentric pair No 1, loss of one of the chromosomes of the subtelocentric pair No 4, and appearance of a large metacentric element) could be explained by: a) a fusion of one of the subtelocentrics of the pair No 4 with one of the acrocentric elements of pair No 5 (the largest of the acrocentric series), which would maintain the size relation between those elements and the new large metacentric chromosome (Figure 3); or b) a pericentric inversion of one of the chromosomes of the metacentric pair No 1 causing the displacement of the centromere from a medium to a terminal location, and maintaining the segment that possesses rDNA cluster at the same position (Figure 4).
A case of small cerebral cyst and pericentric inversion of chromosome 9 that developed schizophrenia-like psychosis.
White (1949) and Coleman (1948) found that within-Urthoptera pericentric inversions were mainly observed in three genera, Trimerotropis, Circotettix and Aerochoreutes (band-winged grasshoppers, Oedipodinae), referring to them as "trimerotropines" to reflect their relatedness [Aerochoreutes was later removed from synonymy to Circotettix (Utte 1984)].
A letter "C" for chromosome 4 denotes the pericentric inversion [ILLUSTRATION FOR FIGURE 2 OMITTED].
Early cytogenetic studies demonstrated that some natural populations from Entre Rios Province showed a temporally stable polymorphism for a pericentric inversion in the [M.sub.4] chromosome pair, which affects chiasma frequency and distribution intra- and interchromosomally (Remis 1989, 1990).
Structural rearrangements (fissions and a pericentric inversion) involving chromosomes 1, 2, 3, 4, and 6 delineate the cytotypes ([ILLUSTRATION FOR FIGURE 2 OMITTED], Sites et al.
pallidipennis populations sited at lower altitudes tend to support larger individuals, where pericentric inversions are more frequent (Colombo 2014).