area showed mild inflammatory cells infiltration.
This substitution has been previously reported as disease-causing (rs76157638; HGMD ID CS024003), but not associated with pericentral
retinal degeneration (PRD) [29-32].
de la ciudad, rodeado por las avenidas Richieri, Cruz Roja, Los Incas y Julio A.
IF analysis showed a novel pattern, involving prevalently the pericentral
zone and extending to the mid-lobule zone of the liver (Figure 1(a)), while sparing the staining of the renal proximal tubular cells (Figure 1(b)).
Hypoperfusion may lead to changes in cortical thickness, as obtained from structural MRI scans, in areas most vulnerable to aging (medial prefrontal and pericentral
cortices) as well as in areas associated with amyloid-aggregation (e.g., occipitotemporal and basal temporal cortices), especially in APOE4 carriers .
On histological examination, for both strains, the CpG/D-galN-treated mice, but not PBS-injected mice, showed numerous inflammatory foci in the pericentral
area with signs of inflammatory liver damage, based on observations of hemorrhage, infiltration of lymphocytes, and scattered eosinophilic degenerative damages of liver cells, which were in good agreement with the similar analysis by Yi et al.
 NASH related cirrhosis was diagnosed based on presence of cirrhosis in patients with evidence of BMI > 28 kg/m2, diabetes, negative viral markers, alcohol less than 20 gm/day in men and < 10 gm/day in females and histological features like lobular or portal inflammation, ballooned hepatocytes with Mallory Denk bodies and fibrosis in a pericentral
vein or zone 3 distribution.