Interictal alterations of the trigeminal somatosensory pathway and periaqueductal
gray matter in migraine.
Although freezing is sufficient to bring about conditioned suppression, it is not necessary for its occurrence: under certain conditions, such as lesions to the periaqueductal
gray (Amorapanth, Nader & LeDoux, 1999), conditioned suppression can occur in the absence of freezing.
These receptors are found in various central nervous system areas that are involved in pain perception and modulation, such as the periaqueductal
grey, the thalamus, and the spinal cord dorsal horn .
Noxious stimulation increased glutamate and arginine in the periaqueductal
gray matter in rats: a microdialysis study.
Western medicine hypothesises that signals from stimulation of peripheral nerve fibres (possibly through acupuncture points) can influence hypothalamic functions via the dorsal periaqueductal
grey fibres, and thereby influence the respiratory centre in the medulla, modifying respiration (Takeshige et al 1993).
2005) found that presynaptic [mu]-receptors localized on the neurons carrying impulses to the CeA and projecting to a midbrain structure called the periaqueductal
gray area decreased GABAergic but not glutamatergic transmission.
There is often involvement of surrounding periventricular and periaqueductal
tissue such as dorsal pons, midbrain, thalamus, or pineal region, and multinodularity or multicentricity may be observed.
Blockade of histamine [H.sub.2] receptors of the periaqueductal
gray and inferior colliculus induces fear-like behaviors.
Associated neurobiological structures and functions associated with the FFFS are the periaqueductal
grey, medial hypothalamus, and amygdala, and serotonergic inputs into these structures.
(35.) Supraspinal structures include the hypothalamus, periaqueductal
gray matter, locus coeruleus, and nucleus raphe magnus.
Brain MRI showed increased T2 signal in the periaqueductal
gray matter, substantia nigra, and trigeminal motor nuclei.
Subcortical regulation: periaqueductal