However, histologic analysis of other vessels, such as the aorta, may be necessary for patients with chronic periaortitis
, including inflammatory abdominal aortic aneurysms and retroperitoneal fibrosis, which are frequently similar in patients with IgG4-related and non-IgG4-related disease (5).
and periarteritis are the most common lesions affecting various medium- to large-sized arteries, including the abdominal aorta, iliac artery, renal artery, and mesenteric artery (57).
* Retroperitoneal fibrosis, frequently occurring as chronic periaortitis
Kawashima et al., "Inflammatory abdominal aortic aneurysm: close relationship to IgG4-related periaortitis
," The American Journal of Surgical Pathology, vol.
In our case, abdominal aneurysms showed findings of chronic periaortitis
(CP) which were characterized by deposition of fibroinflammatory, periaortic tissue with the retroperitoneal tissue.
Vaglio et al., "TLR-4 and VEGF polymorphisms in chronic periaortitis
," PLoS One, vol.
Other common presentations include Riedel's thyroiditis, autoimmune pancreatitis, sclerosing cholangitis, sialadenitis, dacryoadenitis, periaortitis
, an eosinophilic rash, and pseudotumor of the lung, lymph nodes, or orbits.
CT abdomen showed saccular outpouchings from the descending thoracic aorta just above the diaphragm concerning for penetrating atherosclerotic ulcers with periaortitis
Serum antibodies to oxidized, low-density lipoprotein and ceroid in chronic periaortitis
. Arch Pathol Lab Med 1990;114:383.
(88,91-96) Many diseases such as Riedel thyroiditis (RT), Mikulicz syndrome, periaortitis
, multifocal fibrosclerosis, retroperitoneal fibrosis, and idiopathic membranous glomerulonephritis, described as separate entities previously, have now been categorized as part of the IgG4-RD spectrum.