Analysis revealed that C[O.sub.2] laser surgeons had a statistically significant greater risk of acquiring nasopharyngeal warts but were less likely to acquire plantar, genital, and perianal warts
than the Mayo Clinic patient group did, demonstrating that laser plume is a likely means by which HPV can be transmitted to the upper airway, suggesting that those using lasers to treat HPV lesions are at greater risk.
Shinde et al.8 reported a 32% prevalence of STIs in their study, with a majority of 9.3% each of perianal warts
and genital scabies.
The HPV-6 L1-LCR-E5a-E5b genomic variant, identified in perianal warts
and warts removed from pubic region, matched completely in selected L1-LCR-E5a-E5b genomic regions, whereas the genomic variant identified in AGW, removed from the femoral fold, was distinct in the HPV-6 E5a genomic region in two nucleotides and in the HPV-6 LCR region in one nucleotide (Figure 1).
Veregen Ointment 15% is a botanical drug product that is specifically indicated for the topical treatment of external genital and perianal warts
in immunocompetent patients aged 18 years and older, said Dr.
The agent, approved in the United States for treatment of external genital and perianal warts
, has a "rather complex method of action.
Imiquimod iis FDA approved for genital and perianal warts
in patients older than 12 years of age, as well as for actinic keratosis, superficial basal cell carcinoma, and antiviral-resistant herpes simplex virus in patients older than 12 years of age.
The youngest patient was an 8-month-old girl with perianal warts
Imiquimod 5% cream is indicated for the treatment of superficial basal cell carcinoma and actinic keratosis in adults, and external genital and perianal warts
in patients aged 12 years and older.
Imiquimod currently is approved for the treatment of external genital and perianal warts
The trial is expected to start in January 2008 and will include 40 patients with external genital and perianal warts