perianal

(redirected from perianal fistula)
Also found in: Dictionary, Encyclopedia.
Related to perianal fistula: Perianal abscess

perianal

 [per″e-a´nal]
around the anus.

cir·cum·a·nal

(ser'kŭm-ā'năl),
Surrounding the anus.
Synonym(s): perianal, periproctic

perianal

[per′i·ā′nəl]
Etymology: Gk, peri, around; L, anus
pertaining to the area around the anus.

perianal

adjective Around or surrounding the anus.

per·i·a·nal

(per'ē-ā'năl)
Pertaining to the area around the anus.
[G. peri, around + L. anus]

perianal

around the anus.

perianal abscess
under the skin outside the anal canal. Causes sufficient pain to inhibit defecation.
perianal fistula
a syndrome of inflammation, ulceration, and draining sinuses and fistulae in the perianal region of dogs, particularly German shepherd dogs. The specific lesions include fistulae of the anal sinuses, anal sac rupture and fistulae, submucous fistulae and sinuses and fistulae of the rectum. Clinical signs include painful defecation and unpleasant odor. A variety of surgical techniques have been developed, but the condition is very resistant to treatment. Called also anal furunculosis.
perianal gland
modified sebaceous glands found in skin around the anus of dogs. Other regions also contain modified glands, e.g. the perineum, prepuce, thigh, dorsal lumbosacral area and tail base. Called also circumanal glands, hepatoid glands.
perianal gland hyperplasia
most perianal gland enlargements in male dogs are hormone-dependent hyperplasia and regress when the patient is castrated.
perianal gland tumors
nodular hyperplasia, adenomas and carcinomas are common in older male dogs, occurring occasionally in females.
perianal pyoderma
see perianal fistula (above).
perianal sinus
see perianal fistula (above).
perianal warts
papilloma around anus, virus possibly transmitted by veterinarian performing rectal examination.
References in periodicals archive ?
NASDAQ: BLFS), the leading developer, manufacturer and marketer of proprietary clinical grade cell and tissue hypothermic storage and cryopreservation freeze media and a related cloud hosted biologistics cold chain management app for smart shippers("BioLife" or the "Company"), today announced that its customer TiGenix NV, an advanced biopharmaceutical company focused on developing and commercializing novel therapeutics from its proprietary platforms of allogeneic expanded stem cells, recently disclosed that its lead compound Cx601 met the primary endpoint in the Phase III ADMIRE-CD trial of complex perianal fistula in Crohn's Disease patients.
Answer) This is the only question about perianal fistula that I can remember since day one of this magazine.
Surgery was required for 71% of first episodes of perianal fistula vs.
Twenty percent of Crohn's patients have debilitating perianal fistulas, and the quality of life of these patients is severely reduced.
August 7 (SeeNews) - Belgian biopharmaceutical company Tigenix (EBR:TIG) said Friday it had reached an agreement with the US Food and Drug Administration (FDA) on a Special Protocol Assessment (SPA) for its Phase III registration trial of Cx601 in the US for the treatment of complex perianal fistulas in Crohn's disease patients.
Cx601 is Tigenix`s expanded adipose-derived stem cell (eASC) therapy for the treatment of perianal fistulas in Crohn`s disease patients, and the Belgium-based company has chosen Lonza to produce the product for an upcoming Phase III trial in the US.
It is stated that Cx601 is a locally-injected suspension of allogeneic expanded adipose-derived stem cells (eASCs) for the treatment of complex perianal fistulas in crohn s disease patients, currently in phase III of clinical development in Europe.
TiGenixAais also negotiating with a number of parties over commercial rights to its development candidate Cx601, that treats perianal fistulas in Crohn's disease, in non-European countries.
Oral tacrolimus was less effective than infliximab for treating perianal fistulas, said Dr.
Cellerix has three products undergoing clinical trials: Ontaril(R) (Cx401) for the treatment of perianal fistulas, currently in Phase III, Cx501 for skin regeneration, currently in Phase II and Cx601 for the treatment of perianal fistulas, in phase II.
This pivotal, double-blind, placebo controlled study, FHAST1 (Fistula Healing with AST-120), has been designed to determine the efficacy and safety of oral AST-120 in 240 patients with Crohn's disease suffering from perianal fistulas.