They are present in the periacinar
space and have long cytoplasmic processes that surround the acinar structures and ducts of the exocrine pancreas (Omary et al.
PSCs are resident exocrine pancreas cells located in the periacinar
, periductal and perivascular spaces of the pancreas (Omary et al.
A relatively recently described phenomenon, that might be related to the fibro- or myofibroblasts and their products, is the appearance of the so-called periacinar
halos, retraction clefting or cleft-like spaces within a neoplastic prostatic tissue.
Estos efectos provocan una alteracion inicial de la circulacion intrahepatica que culmina con necrosis de hepatocitos y hemorragia periacinar
The intensity of cytoplasmic reactivity of the antibodies within acinar epithelium and periacinar
stromal cells was subjectively scored as: 0=negative, 1=discrete, 2=moderate and 3=intense.
Los cortes histologicos evidenciaron ictericia en 22 casos, necrosis periacinar
en 25 casos, respuesta micronodular en 16 casos, y fibrosis hepatica segmental en 12 casos (Fig.
The stroma in atrophy is altered by a pale fibrosis (Figure 1, E), with periacinar
collagen deposition, which can impart a sclerotic appearance.
IL-6 secretion by human pancreatic periacinar
myofibroblasts in response to inflammatory mediators.
2D, F, I): a) gametogenic or acinar; b) perigametogenic or periacinar
and c) intergametogenic or interacinar.
stellate shaped cells in rat pancreas--identification, isolation, and culture.
All animals showed hepatocytic microvesicular lipid accumulation (foamy cytoplasm), and 84% showed sharply demarcated macrovesicular lipid vacuoles in mainly periacinar
(zones 2-3) hepatocytes (Table 1, Figure 2).
Histopathology revealed intense congestion of the liver and, in periacinar
zone the hemorrhage was more evident.