Cardiac valvulopathies and pulmonary-retroperitoneal fibrosis may develop with long-term use and high doses of ergot derivative dopamine agonists, particularly pergolide
and cabergoline (17,18).
Les principales causes de la FRP secondaire (1) Medicaments Methysergide Pergolide
Bromocriptine Ergotamine Methyldopa Hydralazine Analgesiques Beta-bloquants Tumeurs malignes Tumeurs carcinoides Lymphomes Hodgkiniens et non Hodgkiniens Sarcomes Cancers : colon, prostate, poumon, estomac Infections Tuberculose Histoplasmose Actinomycose Radiotherapie Seminome testiculaire Carcinome du colon Carcinome pancreatique Chirurgie Lymphadenectomie Colectomie Hysterectomie Anevrysectomie aortique Autres Histiocytose Maladie de l'Erdheim-Chester Amylose Traumatismes Lavement baryte Tableau 2.
SOME DRUGS THAT CAN CAUSE OR EXACERBATE HEART FAILURE Condition Drugs Arrhythmia dronedarone, flecainide, disopyramide, sotalol Cancer anthracydines and many other agents Depression citalopram, lithium Diabetes thiazolidinediones, dipeptidyl peptidase-4 inhibitors Fungal infections amphotericin B Hypertension doxazosin, diltiazem, verapamil, moxonidine Malaria chloroquine, hydroxychloroquine Migraines ergotamine, methysergide Pain prescription and nonprescription NSAIDs Parkinson's pergolide
, pramipexole, bromocriptine Platelet disorders anagrelide, cilostazol Pulmonary disease bosentan, epoprostenol, albuterol Rheumatologic TNF-a inhibitors diseases
reported in the journal Sleep that "Levodopa with decarboxylase inhibitors, and the dopaminergic agonists pergolide
, pramipexole, and ropinirole are effective in the treatment of RLS and PLMD.
plus ondansetron treatment was able to reverse a previously established cocaine sensitisation (72) and attenuated methamphetamine reinstatement (relapse) in rats.
who showed significant correlation between psychotic symptoms in PD patients and the use of pergolide
, but not ropinirole, pramipexole, or cabergoline (dopamine agonists).
, atomoxetine, and memantine are also used, even though they are not so common.
Parkinson's disease drug pergolide
, a dopamine agonist, because it
Various researches suggested encouraging results of dopamine agonists bromocriptine and pergolide
combined with an antidepressant in treatment resistant depression (15,16).
The effects of pergolide
on memory and oxidative stress in a rat model of Parkinson's disease.
A multicenter double-blind placebo-controlled trial of pergolide
as an adjunct to Sinemet in Parkinson's disease.
Many low- and middle-income countries do not have ready access to the newer alpha-2 agonists that are currently considered first-line drugs for Tourette's (such as pergolide
, tetrabenazine and topiramate), so antipsychotic medications are the most commonly used drugs for the condition despite the risk of metabolic and other side effects associated with chronic use of these medications.