First, we employed an isolated perfused
lung model to mimic any hemodynamic effects on lung injury, but the model could not provide information regarding the interactions with other organs.
The role of anion exchanger on pulmonary vascular response to sustained alveolar hypoxia in the isolated perfused
Opie, Effects of Insulin on the Pattern of Glucose Metabolism in the Perfused
Working and Langendorff Heart of Normal and Insulin- Deficient Rats, Biochem Journal, 115, 537 (1969).
Spencer, "Differences in the bioenergetic response of the isolated perfused
rat heart to selective [beta]1- and [beta]2-adrenergic receptor stimulation," Circulation, vol.
Blood from the normal pump twin reaches the perfused
twin through arterio-arterial anastomosis flows through acardiac twin in reverse course, then returns to pump twin through veno-venous anastomosis (TRAP).
When the hippocampus was perfused
with ACSF, the basal concentration of extracellular glutamate was decreased in the presence of DHMBA (1 mmol [1.
Harvest and Ex vivo Perfusion of Hearts: Hearts were harvested and perfused
ex vivo for hemodynamic measurements using the Langendorff system.
All hearts had been perfused
for 25 min when the baseline measurements were taken.
The design of the Isolated Perfused
Lung series of lung systems allows for a higher reproducibility and lower inter-user variability than traditional tubing/glassware systems.
Animals were injected with BrdU after 4 weeks of treatment to label dividing cells and perfused
4 weeks later to allow time for the new cells to differentiate.
The device is the first completely automated liver perfusion device of its kind: the organ is perfused
with oxygenated red blood cells at normal body temperature, just as it would be inside the body, and can for example be observed making bile, which makes it an extraordinary feat of engineering.
Microvascular permeability, leukocyte adhesion to venular walls, perfused
capillary length, and capillary red blood cell velocity (V(RBC)) were evaluated by computer-assisted methods.