The perforating dermatoses are a diverse group of diseases that include four types: elastosis perforans serpiginosum, Kyrle disease, perforating folliculitis
, and reactive perforating collagenosis (RPC).
The evolution of perforating folliculitis
in patients with chronic renal failure.
is characterized by adult-onset scaly follicular papules with a white central keratotic plug (may contain curled hair) on the extensor surfaces of the extremities and buttocks.
Finally, perforating disorders with transepidermal elimination of elastin (elastosis perforans serpiginosa, perforating folliculitis
, perforating pseudoxanthoma elasticum) may resemble HLE, but these lesions contain neutrophils and histiocytes with fewer lymphocytes and typically do not demonstrate vacuolar interface changes (Figure 7, B).
This is thought to be an isotopic response that describes the occurrence of a new skin disorder at the site of another lesion that has already healed and is unrelated to primary dermatosis.6 KD is one of the perforating skin diseases that represents a heterogeneous group of disorders characterized by transepithelial elimination of dermal structures.10 Primary perforating disorders include Kyrle's disease, elastosis perforans serpiginosa, perforating folliculitis
and reactive perforating collagenosis.11
in association with hemodialysis.