perforating disorder

perforating disorder

Any of several rare conditions associated with diabetes mellitus and/or chronic kidney disease in which dermal components, such as collagen or elastin, protrude through the epidermis. The perforating disorders include elastosis perforans serpiginosa, Kyrle disease, perforating folliculitis, and reactive perforating collagenosis, but some experts believe that all of these conditions reflect the same disease.
References in periodicals archive ?
The results were consistent with a perforating disorder.
In contrast to other perforating disorders, the extruded material is predominantly keratin rather than elastic fibers or collagen.
Histologic analysis suggested a perforating disorder but could not rule out skin cancer.
Acquired reactive perforating disorder associated with chronic kidney disease.
While other studies showed acquired perforating disorders in 4.
8 showed ecchymosis in 9% and perforating disorders like acquired perforating disorder in 4.
Xerosis, pruritus, half-and-half nails, cutaneous hyperpigmentation, pallor and perforating disorders are common manifestations of ESRD.
Other less common, specific manifestations of CKD patients on hemodialysis like acquired perforating disorders (1.
Cutaneous manifestations of diabetes are classified into four categories: Skin lesions with strong-to-weak association to diabetes (necrobiosis lipoidica, diabetic dermopathy, diabetic bullae, yellow skin, eruptive xanthomas, perforating disorders, acanthosis nigricans, oral leucoplakia, lichen planus), infections (bacterial, fungal), cutaneous manifestations of diabetic complications (microangiopathy, macroangiopathy, neuropathy) and skin reactions to diabetic treatment (Sulphonylureas or insulin).
Other entities with exuberant pseudoepitheliomatous hyperplasia not typically considered interface processes may rarely enter the differential, including deep fungal infections, the halogenodermas (bromoderma, iododerma), and some perforating disorders.
10 Primary perforating disorders include Kyrle's disease, elastosis perforans serpiginosa, perforating folliculitis and reactive perforating collagenosis.
Perforating disorders Perforating disorders of renal disease or acquired perforating disorders (APD); the term has been used to describe the hyperpigmented papules, up to 1 cm in diameter, with a central keratinous plug in patients of CRF.

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