perforating disorder

perforating disorder

Any of several rare conditions associated with diabetes mellitus and/or chronic kidney disease in which dermal components, such as collagen or elastin, protrude through the epidermis. The perforating disorders include elastosis perforans serpiginosa, Kyrle disease, perforating folliculitis, and reactive perforating collagenosis, but some experts believe that all of these conditions reflect the same disease.
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with sub groups of perforating disorder collangenosis, perforating folliculitis, ellastosis perforans serpiginosa, and folliculitis in cutem penetras.
Other entities with exuberant pseudoepitheliomatous hyperplasia not typically considered interface processes may rarely enter the differential, including deep fungal infections, the halogenodermas (bromoderma, iododerma), and some perforating disorders.
Finally, perforating disorders with transepidermal elimination of elastin (elastosis perforans serpiginosa, perforating folliculitis, perforating pseudoxanthoma elasticum) may resemble HLE, but these lesions contain neutrophils and histiocytes with fewer lymphocytes and typically do not demonstrate vacuolar interface changes (Figure 7, B).
Dermatological diseases in which Koebner's phenomenon occurs Contact dermatitis Molluscum contagiosum Darier's disease Pellagra Dermatographism Perforating disorders Eruptive xanthoma Pityriasis rubra pilaris Erythema multiforme Porokeratosis Henoch-Schonlein purpura Psoriasis * Kyrle's disease Reactive perforating collagenosis Lichen nitidus Rhus dermatitis * Lichen planus * Verrucae * Lichen sclerosus et atrophicus Vitiligo * Most frequently seen Table 2.

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