perflubron

per·flu·bron

(per-flū'bron),
Generic name for perfluorooctyl bromide.

perflubron

LiquiVent® Neonatology A highly oxygenated perfluorocarbon liquid intrapulmonary ventilating agent, used in neonates with severe RDS and adults with acute hypoxemic respiratory failure, which may prevent O2 toxicity, ↓ barotrauma due to improved dynamic compliance, ↑ oxygenation. See Liquid ventilation, Respiratory distress syndrome.
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References in periodicals archive ?
He tried a rebreather (basically a big rubber tube pushed down his throat, made Home Depot-style); then the liquid breathing chemical perflubron; and even researched heart-lung surgery.
Steinhorn, "Partial liquid ventilation with perflubron attenuates in vivo oxidative damage to proteins and lipids," Critical Care Medicine, vol.
Indirect ultrasonographic lymphography with perflubron emulsion.
The PFC liquids used to support pulmonary gas exchange are a type of synthetic liquid fluorinated hydrocarbon (hydrocarbons with the hydrogen replaced by fluorine, and for perflubron where a bromine atom is added as well) with high solubility for oxygen and carbon dioxide.
Oxygent (perflubron emulsion) is a patent-protected, stable, and concentrated perfluorochemical (PFC)-based synthetic oxygen therapeutic developed by Alliance, which has been evaluated in late-stage clinical studies for avoidance of red blood cell transfusions during surgery.
have met with selected European regulatory authorities to review the clinical development plans for Oxygent(TM) (perflubron emulsion), an intravascular oxygen carrier intended to avoid the need for donor blood in elective surgery.
Alliance Pharmaceutical Corp., San Diego, has announced that its initial analysis of the data from a Phase 3 study conducted in Europe with Oxygent(TM) (perflubron emulsion), an intravenous oxygen carrier, demonstrated that the product provided a statistically significant reduction in the need for donor blood in the total study population of 492 patients undergoing a variety of general surgery procedures.
A new oxygen-bearing lubricant, called perflubron, has been tested on 13 premature infants with severe surfactant deficiency.
Thanks to this oxygen-bearing lubricant, called perflubron, the baby was one of eight to survive a crisis known as surfactant deficiency.
Oxygent (perflubron emulsion) is a patent-protected synthetic oxygen carrier that Alliance has evaluated in late-stage clinical studies for avoidance of red blood cell transfusions during surgery.
Oxygent (perflubron emulsion), an intravenous oxygen carrier, is being developed in the United States, Canada, and Europe in conjunction with Baxter Healthcare Corporation.
Shepherd and Steinke (1) reported that perflubron emulsion, a potential blood substitute soon to be in clinical use, interferes with measurements by several CO-oximeters.