peptoid


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pep·toid

(pep'toyd),
A peptide with one or more non-amino acyl groups (for example, sugar, lipid) covalently linked to the peptide.
References in periodicals archive ?
GU81, a VEGFR2 antagonist peptoid, enhances the anti-tumor activity of doxorubicin in the murine MMTV-PyMT transgenic model of breast cancer.
Peptoid microarrays provide an alternative approach to overcome the limitations imposed by antigen selection during the construction of antigen microarrays for biomarker discovery.
The acquisition of OURLab will also help the company in accelerating the development and introduction of other key tests, including such using OPKO's peptoid technology, the buyer's chairman and CEO Phillip Frost said.
The acquisition of OURLab will also help the company in accelerating the development and introduction of other key tests, including such using OPKOa[euro](tm)s peptoid technology, the buyera[euro](tm)s chairman and CEO Phillip Frost said.
With this in mind, the peptoid pieces were robotically synthesized, processed, and then added to a solution that fosters self assembly.
The OURLab structure will also be helpful in speeding the development and introduction of other important tests, including newly discovered antibody-based tests which utilize OPKO's unique peptoid technology.
New technologies, such as the peptoid combinatorial platform being developed by OPKO Health, offer new and more rapid advances in this field.
In addition to the automated approach of synthesizing novel chemical or peptoid libraries, Chiron employs solid phase synthesis technology using the mimotopes "multi-pin" approach in the search for active pharmaceutical lead compounds.
Part II then discusses synthesis and particular mimetic molecules in more detail, including bioisosteres, solid-phase synthesis, combinatorial approaches, click chemistry with triazole scaffolding, peptoids, sugar amino acids as scaffolds, cyclic alpha-amino acids as proline mimics, beta-turn mimetics, and foldamers, including material on both structure-function relationships and synthesis.
The companies will now join forces to develop a pipeline of proprietary peptoids and other molecules for diagnostic and therapeutic products, said Phillip Frost, chairman and chief executive officer of OPKO.
These peptoids have many advantages; they can be modified easily and can be produced quickly in relatively large amounts at lower cost.
The particular peptoids that retained more antibodies from the blood samples of the diseased animals were identified as potential agents for capturing diagnostically useful molecules.