peptidomimetics

(pĕp″tĭ-dō-mĭ-mĕt′ĭks, pĕp-tīd′ō-mī-) [″ + ″]

The synthetic alteration of a natural peptide to make a new molecule that works in a specific biological or therapeutic application.

References in periodicals archive ?

is a private company focused on developing the use of peptidomimetics as a novel approach to treating ophthalmic diseases with high unmet medical needs.

Allergan Enters Into Licensing Agreement with Mimetogen Pharmaceuticals to Develop and Commercialize Tavilermide (MIM-D3) Topical Dry Eye Treatment

1) is a feasible structural modification of biologically active peptides for obtaining peptidomimetics with an increased effective lifetime in biological systems [1, 2].

Synthesis of the Fmoc-aza-Arg[(Boc).sub.2] precursor via hydrazine alkylation/Fmoc-aza-Arg[(Boc).sub.2] prekursori suntees hudrasiini alkuulimise teel

After introducing the paradigm, the book covers methodology useful to diversity-oriented synthesis including multicomponent and "domino" strategies, cycloadditions, phosphine organocatalysis, peptidomimetics, solid-phase synthesis, and macrocycles.

Diversity-oriented synthesis; basics and applications in organic synthesis, drug discovery, and chemical biology

Beginning with a comprehensive chapter outlining computational methods in peptide and protein design, it goes on to explore peptidomimetics, design of cyclic peptides, the role of carbohydrates in the process of design, and de novo methods.

Peptide and protein design for biopharmaceutical applications

Keeping close ties with Ukrainian academic research centers, Enamine explores a variety of prospective topics in contemporary organic chemistry, such as assymmetric synthesis, synthesis of fluorescent dyes and peptidomimetics, and supports other projects aimed at the development of fundamental research in organic chemistry.

Carna Biosciences and Enamine Sign Collaboration Agreement

The Company also has a rich pipeline of small molecule compounds in preclinical development, consisting primarily of new chemical entities based on 2-methoxyestradiol-related structures (steroidal and non-steroidal analogs) and chemically-derived small molecules from peptides -- peptidomimetics.

EntreMed announces gene target delivery licensing deal with Oxford BioMedica

The company has distinguished itself as an early innovator of combinatorial chemistry techniques for drug discovery and as one of the world's largest manufacturers of custom peptides, peptidomimetics and small molecule libraries.

MITOKOR ACQUIRES CHIRON TECHNOLOGIES PTY. LTD."MIMOTOPES"

Treco will present "Direct selection of cyclic peptidomimetics from in vitro display libraries" at TIDES, the Oligonucleotide and Peptide Research, Technology and Product Development Conference on Wednesday, May 23, 2012, at 10:00 am PT at the Mandalay Bay Resort & Casino in Las Vegas, NV.

Ra Pharmaceuticals Unveils Hereditary Angioedema as Lead Program Leveraging Its Cyclomimetic Discovery Platform

We proposed the preparation of a novel and diverse library of conformationally constrained peptidomimetics containing quaternary stereocenters derived from B/C/P approach with increased biological relevance.

DOS-PEPTIDOMIMETICS: Diversity-Oriented Synthesis of Conformationally Constrained Peptidomimetics

The chapter entitled, "Microwave-Enhanced Synthesis of Peptides, Proteins and Peptidomimetics," was authored by Jonathan M.

New Book Chapter from CEM on Microwave Peptide Synthesis

At present his main research fields are design, synthesis, and testing of biomimetic organic compounds and peptidomimetics.

Introducing the renewed Proceedings

Valentis' core technologies include multiple gene delivery and gene expression systems and PEGylation technologies designed to improve the safety, efficacy and dosing characteristics of genes, proteins, peptides, peptidomimetics, antibodies, replicating and non replicating viruses and liposomes.