Walfield et al., "Effective synthetic
peptide vaccine for foot-and-mouth disease in swine," Vaccines, vol.
At present, antivirus, anticancer, antimalaria, contraception, and other
peptide vaccines are under clinical trials [62, 69-72, 74, 75].
Immunized group mice were immunized subcutaneously with 100 [micro]L of antigen-adjuvant suspension containing 20 [micro]g
peptide vaccine emulsified in complete Freund's adjuvant (CFA) (Sigma).
Peptide Vaccines. Iversen [31] conducted a preliminary phase II study of a combined treatment with a vaccine (IDO + survivin peptides, combined with montanide, imiquimod, and granulocyte macrophage colony-stimulating factor (GM-CSF) as adjuvants) plus the chemotherapeutic agent temozolomide (TMZ).
The patients who received ipilimumab had a median survival of 10.1 months, compared with 6.4 months in those receiving the
peptide vaccine gp100 alone.
Phase I Trial of Tyrosinase, gp100 and MART-1
Peptide Vaccine with Incomplete Freund's Adjuvant for Resected High-Risk Melanoma, Clinical Cancer Research October 1999 5; 2756
Immunologic and therapeutic evaluation of a synthetic
peptide vaccine for the treatment of patients with metastatic melanoma.
The study will investigate the clinical efficacy and safety of Celldex's epidermal growth factor receptor variant III (EGFRvIII)
peptide vaccine CDX-110 added to standard-of-care in patients with newly diagnosed glioblastoma multiforme (GBM) that express the variant III mutation of the EGFR receptor.
Induction of influenza type A virus-specific resistance by immunization of mice with a synthetic multiple antigenic
peptide vaccine that contains ectodomains of matrix protein 2.
peptide vaccine technology in the areas of autoimmunity and allergies.
Research results for the new treatment, known as a
peptide vaccine, will be unveiled at the Royal Society of Medicine in London today.
The researchers then treated mice with either the seven-amino-acid peptide or the
peptide vaccine and exposed them to strains of influenza from the past 10 years.
