peptide antibiotic

peptide antibiotic

antibiotic composed of peptides; the antibacterial action is based on the physical disruption of cell membranes.

pep·tide an·ti·bi·ot·ic

(pep'tīd an'ti-bī-ot'ik)
An antibiotic composed of peptides; its antibacterial action is based on the physical disruption of cellular membranes.
References in periodicals archive ?
* McCafferty DG, Cudic P, Yu MK, Behenna DC, Kruger R (1999) Synergy and duality in peptide antibiotic mechanisms, Curr Opin Chem Biol, 3: 672-680.
Schroder, "Isolation and characterization of human [beta]-defensin-3, a novel human inducible peptide antibiotic," The Journal of Biological Chemistry, vol.
Optimization of conditions for antimicrobial peptide production: Conditions such as temperature, nitrogen source, incubation time and pH were optimized for the maximum production of peptide antibiotic. For temperature optimization, conical flasks containing BHI broth with 1 % inoculums culture were maintained at different temperatures (30, 35 and 40 C) for overnight.
Some rrs mutations also confer resistance to the cyclic peptide antibiotic CAP .
Dale, "Expression of the peptide antibiotic human [beta]-defensin 1 in cultured gingival epithelial cells and gingival tissue," Infection and Immunity, vol.
[17] Martin, N.I., et al., Isolation, structural characterization, and properties of mattacin (polymyxin M), a cyclic peptide antibiotic produced by Paenibacillus kobensisM.
(2008) determined another actinomycete peptide antibiotic, valinomycin isolated from Streptomyces sp.
licheniformis strain, 189, isolated from a hot spring environment in the Azores, Portugal, was found to strongly inhibit growth of Gram-positive bacteria by producing peptide antibiotic (Mendo et al., 2004).
Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic. J Biol Chem 2001;276:5707-13.