peptide YY


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Related to peptide YY: leptin, amylin

peptide YY

pep·tide YY

(pep'tīd)
A hormone released by the small intestine to signal the brain to stop eating.

peptide YY

An appetite-regulating protein released by L cells of the mucosa of the gastrointestinal tract in response to a meal. It binds to cells in the arcuate nucleus of the brain, decreases the desire to eat, and creates a feeling of fullness.
See also: peptide
References in periodicals archive ?
The agreement includes exclusive commercial rights to issued United States Patent 5,604,203, which relates to analogs of Peptide YY, or peptide derivatives, and uses thereof as therapeutic agents in the treatment of gastroenterological disorders; issued United States Patents 6,013,633, 6,235,718 and 6,737,408, which relates to compounds for control of appetite; and United States Patent 6,046,167, which relates to analogs of Peptide YY.
El Akkary and his colleagues noted that an increase in peptide YY might explain the findings.
Peptide YY is a naturally produced hormone associated with the modulation of appetite circuits in the brain.
Results were presented on the effects of EndoBarrier on two gastrointestinal hormones, gut peptides glucagon-like peptide-1 (GLP-1) and peptide YY (PYY), and other diabetes measures.
Previous studies on that gut hormones, such as peptide YY (PYY) and glucagon-like peptide (GLP-1), has shown that their release after a meal acts on the brain and induces satiety and meal termination.
As food enters your stomach, it stimulates production of two hormones - peptide YY and oxyntomodulin - that create a feeling of fullness.
A study of meal-stimulated responses of insulin, ghrelin, peptide YY, glucagon-like-peptide-1, and pancreatic polypeptide in humans and rodents following different bariatric surgical techniques found that gastric bypass patients had early and exaggerated insulin responses, potentially mediating the improved glycemic control in patients with diabetes (Ann.
Bothell, WA) announced it has acquired exclusive worldwide rights to the Cedars-Sinai Medical Center (Los Angeles, CA) (CSMC) Peptide YY patent, patent applications, and proprietary know-how estate to support ongoing commercialization efforts of Nastech's investigational PYY 3-36 Nasal Spray for Obesity.
In addition, animal studies have shown that the fermentation of Hi-maize resistant starch in the large intestine turns on the genes that make satiety hormones glucagon-like peptide-1 (GLP-1) and peptide YY (PYY), and that these hormones remained elevated for 20+ hours.