pentylenetetrazol


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Related to pentylenetetrazol: Metrazol

pen·ty·lene·tet·ra·zol

(pen'ti-lēn-tet'ră-zol),
A powerful CNS stimulant; has been used to cause generalized convulsion in the shock treatment of emotional states and as a respiratory stimulant; mainly used in experimental studies of seizure mechanisms and the search for new anticonvulsant drugs.

pentylenetetrazol

(pĕn′tə-lēn′tĕt′rə-zôl′, -zōl′, -zŏl′)
n.
A drug, C6H10N4, that is a central nervous system and respiratory stimulant, used experimentally primarily to induce seizures for pharmaceutical research.

pentylenetetrazol

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References in periodicals archive ?
Electrocorticographical observation of seizures induced by pentylenetetrazol (PTZ) injection in rats.
Studies in animal models show efficacy of Passiflora extracts and flavonoid fractions against pentylenetetrazol (PTZ) induced seizures (Speroni and Minghetti 1988; Speroni and Billi 1996; Nassiri-Asl et al.
Pilocarpine (300mg/kg ip), preceded by methylscopolamine (l mg/kg, sc) and pentylenetetrazol (PTZ, 50 mg/kg ip) were used to induce seizures as described previously (Lian et al.
Pentylenetetrazol (PTZ), a selective blocker of the chloride channel coupled to the GABAA receptor complex (Sejima et al.
Industrias Quimicas), valproic acid (Abbot Laboratorios do Brasil), baclofen (Biogalenica Quimica e Farmaceutica Ltda--CibaGeigy), diazepam (Roche Produtos Quimicos e Farmaceuticos), phenobarbital (Rhodia Produtos Quimicos e Farmaceuticos), pentylenetetrazol (Sigma Chemical Co.