Briefly, after SD rats were anesthetized with pentobarbitone
sodium (50 mg/kg, i.
Stress in mice increases intrinsic pentobarbitone
sensitivity by a predominantly pharmacodynamic mechanism.
Lagos, Nigeria); Pentobarbitone
Na (BDH chemicals Ltd, England).
The rats were anaesthetized with sodium pentobarbitone
at 40 mg/kg bw dose (Neon Laboratories, India).
Ten pregnant adult Sprague Dawley (SD) rats at 18 to 22 days' gestation and 10 non-pregnant adult female SD rats were exsanguinated by bleeding from the femoral artery under pentobarbitone
2 ml/kg Stresnil (SmithKline Beecham Animal Health, Auckland, New Zealand) 20 min prior to slaughter, and euthanised by intravenous injection of 125 mg/kg sodium pentobarbitone
(Chemstock Animal Health, Christchurch, New Zealand).
Briefly, adult Wistar rats were anaesthetized by injecting sodium pentobarbitone
Anaesthesia was subsequently induced with pentobarbitone
sodium (20 mg x [kg.
At end of the experimental period (30 clays), all the animals were fasted overnight and sacrificed by cervical decapitation under pentobarbitone
sodium (60 mg/kg) anaesthesia.
The animals were killed at the end of the study with pentobarbitone
100 mg/kg (IV).
2005), groups of mice (n = 10) were treated with PEF and the vehicle 60 min before injection of sodium pentobarbitone
(45 mg/kg, i.
After a water-only overnight fast, male Sprague-Dawley rats (368-442g) from the Central Animal Breeding House of the University of Queensland were anaesthetised with sodium pentobarbitone
60 mg/kg IP and ventilated via a tracheostomy with air/oxygen and isoflurane using a Harvard Rodent Ventilator (Model 683, Southnatick, MA, U.