2015: SA became the first country in Africa to introduce a fully liquid hexavalent vaccine (6-in-1) by replacing the pentavalent
(5-in-1) and hep B vaccines.
It needs mention that the Government of Gujarat introduced the pentavalent
vaccine in UIP in January 2013 and OVP for multi-dose vials was made available from April 2013 in Gujarat.
Mohapatra S, Hajjaran H et al and Thakur CP et al, alongwith several other investigators have demonstrated decreasing efficacy, emerging resistance, rising treatment failure rates with pentavalent
antimony compounds in vivo and in vitro studies11,12.
In this context, this study was planned to assess mother's knowledge on routine vaccination with special focus on pentavalent
vaccine and the extent to which mothers have been informed regarding the newer pentavalent
Consequently, the infants will be given Pentavalent
shots at these 3 intervals each containing the five antigens.
After the introduction of Pentavalent
vaccine (in November 2012) that includes DPT, HepB V and Heamophyllus influenza (Hib) vaccines was received by children instead of DPT & HBV.
antimonials: new perspectives for old drugs.
antimonial drugs are rapidly eliminated through the kidneys, (15) so their use should be avoided in patients with renal dysfunction, due to cardiotoxicity and renal function worsening.
Sanofi Pasteur, the vaccines division of Sanofi (NYSE:SNY), stated on Monday that its paediatric pentavalent
vaccine Shan5 has been awarded prequalification status from the World Health Organisation (WHO).
Data from the first of the new studies show a slight but statistically significant increase in intussusception risk associated with use of Merck's pentavalent
vaccine, RV5 (RotaTeq) (N.
Since the MenAfriVac rollout (2010-2014), there has been no reported case in countries with high vaccine coverage," he said, noting that wide coverage in the use of vaccines such as pentavalent
, pneumoccocal and rotavirus is also having a huge impact.
In August 2013, Indonesia officially rolled out a pentavalent
vaccine designed to immunise newborns against five diseases: diphtheria, whooping cough, tetanus, hepatitis B and haemophilus influenza type B.