pentamidine


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Related to pentamidine: Pentamidine isethionate

pentamidine

 [pen-tam´ĭ-dēn]
an antiinfective used as the isethionate salt, administered intravenously or intramuscularly in treatment of early African trypanosomiasis and leishmaniasis, and intravenously, intramuscularly, or by oral inhalation in treatment and prophylaxis of Pneumocystis cariniipneumonia.

pentamidine

/pen·tam·i·dine/ (pen-tam´ĭ-dēn) an antiinfective used as the isethionate salt in the treatment of pneumonia, leishmaniasis, and early African trypanosomiasis.

pentamidine

A drug used in the treatment of PNEUMOCYSTIS CARINII PNEUMONIA and TRYPANOSOMIASIS. It was the exceptional demand for pentamidine in 1981that heralded the onset of the AIDS pandemic. The drug is on the WHO official list. A brand name is Pentacarinat.
References in periodicals archive ?
04 uM, respectively, when compared with the standard pentamidine having IC50 value 5.
Bilateral pneumothoraces hasten mortality in AIDS patients receiving secondary prophylaxis with aerosolized pentamidine.
Symptomatic hypocalcemia and hypomagnesemia with renal magnesium wasting associated with pentamidine therapy in a patient with AIDS.
c) Individual taking medication like Glucocorticoids, Thyroid hormone, Diazoxide, Phenytoin, pentamidine, OCP.
TbAQP2 knockout cells also were found to be cross-resistant to melarsoprol and pentamidine (Baker et al.
braziliensis parasites usually fail to respond to pentamidine isethionate, the first-line treatment of L.
Other medications used for treatment include amphotericin B, pentamidine, paromomycin, and antifungals.
In contrast, the cells treated with pentamidine (Figure 1(c)) show intense decrease in the fluorescence represented by PE, suggesting a loss of mitochondrial membrane potential which may indicate apoptosis of the parasites analyzed.
1011 Second-line treatments with intravenous amphotericin B deoxycholate (AB) and pentamidine are expensive and potentially toxic; paromomycin and oral miltefosine are not yet available in Pakistan.
Extra-pulmonary Pneumocystis infection occurs in HIV-infected patients on pentamidine prophylaxis or in advanced HIV infection without prophylaxis, even without pulmonary involvement.