pentamidine


Also found in: Dictionary, Wikipedia.
Related to pentamidine: Pentamidine isethionate

pentamidine

 [pen-tam´ĭ-dēn]
an antiinfective used as the isethionate salt, administered intravenously or intramuscularly in treatment of early African trypanosomiasis and leishmaniasis, and intravenously, intramuscularly, or by oral inhalation in treatment and prophylaxis of Pneumocystis cariniipneumonia.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

pentamidine

A drug used in the treatment of PNEUMOCYSTIS CARINII PNEUMONIA and TRYPANOSOMIASIS. It was the exceptional demand for pentamidine in 1981that heralded the onset of the AIDS pandemic. The drug is on the WHO official list. A brand name is Pentacarinat.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005
References in periodicals archive ?
[20.] "Medicare Program: Payment for Home Intravenous Drug Therapy Services," Federal Register, 11 November 1989; City of New York, Department of Consumer Affairs, Making a Killing on AIDS: Home Health Care and Pentamidine, May 1991.
Girard, P.-M., Landman, R, Gaudebout, C., et al.: Dapsone-Pyrimethamine Compared with Aerosolized Pentamidine as Primary Prophylaxis Against Pneumocystis Carinii Pneumonia and Toxoplasmosis in HIV Infection.
These conditions are likely to present more of a problem now that the once-fatal pneumocystis is being treated prophylactically with AZT and pentamidine, and the life expectancy of PWAs is increasing.
His private doctor also gives him aerosol pentamidine, with the trial's agreement.
Evatt told Sandy Ford to be alert for any pentamidine orders that might list hemophilia as an underlying medical condition, and the uneasy months of waiting began.
Keywords: Synthesis, Biscoumarins, In vitro, Anti-leishmanial activities, Pentamidine
However, appropriate therapy is not well defined; success has been sparsely reported with the simultaneous use of azoles, flucytosine, pentamidine, sulfazidine, macrolide antimicrobial drugs, phenothiazines, and miltefosine (2,7,10).
Other causes include the administration of [beta]-blockers, digoxin, non-steroidal anti-inflammatory drugs (NSAIDs), trimethoprim or pentamidine.
Other medications used for treatment include amphotericin B, pentamidine, paromomycin, and antifungals.
Other drugs such as pentamidine, amphotericin B and miltefosine have limited use due to their high cost, severe side effects or resistance (Sanchez-Canete et al., 2009; WHO, 2010).
Other drugs used to treat leishmaniasis include pentamidine and amphotericin B, but the use of these drugs has been limited due to their high toxicity and cost [11].
In 1999, Oliva and colleagues successfully treated a patient with widely disseminated acanthamoebiasis following a single lung transplant for sarcoidosis with a combination of pentamidine, 5-fluorocytosine, itraconazole, and topical chlorhexidine gluconate-ketoconazole cream for skin lesions.