Even among Thai allergists themselves, penicillin skin test is mainly performed by using penicillin G alone and the use of penicilloyl-polylysine and minor determinant mixture is mostly limited for research purposes.
Regarding basic knowledge of penicillin skin testing for diagnosis of an immediate reaction, less than half of non-allergists (29.1%) have accurate knowledge on the appropriate recommended skin test reagents (penicilloyl-polylysine and minor determinants) and only 5.1% of them know how to correctly interpret penicillin skin test results according to the ENDA recommendation (an increase in wheal diameter greater than 3 mm read 15-20 minutes after the test compared to the initial wheal size) .
The very limited usefulness of skin testing with penicilloyl-polylysine
and the minor determinant mixture in evaluating nonimmediate reactions to penicillins.
Hem ENDA hem de Amerika Alerji Astim Immunoloji Akademisi beta laktamlarla olusan hizli reaksiyonlann tanisinda penicilloyl-polylysine
(PPL) ve minor determinant kansimi (MDM) ile deri prik testinin ilk sirada oldugunu belirtmektedirler (32).
Evaluation of penicillin hypersensitivity: value of clinical history and skin testing with penicilloyl-polylysine
and penicillin G.
Brown BC, Price EV, Moore MB: Penicilloyl-polylysine
as an intradermal test of penicillin sensitivity.