penicilloyl-polylysine

penicilloyl-polylysine

(pen?i-sil'o-il?pol?i-li'sen?)
The major antigenic determinant of penicillin. It is used in skin testing for penicillin sensitivity.

Patient care

When it is injected intradermally into a sensitive person, an allergic reaction occurs within 20 min. Tested patients should be monitored for wheals, hives, angioedema, or anaphylaxis.

Synonym: benzylpenicilloyl polylysine
References in periodicals archive ?
Even among Thai allergists themselves, penicillin skin test is mainly performed by using penicillin G alone and the use of penicilloyl-polylysine and minor determinant mixture is mostly limited for research purposes.
Regarding basic knowledge of penicillin skin testing for diagnosis of an immediate reaction, less than half of non-allergists (29.1%) have accurate knowledge on the appropriate recommended skin test reagents (penicilloyl-polylysine and minor determinants) and only 5.1% of them know how to correctly interpret penicillin skin test results according to the ENDA recommendation (an increase in wheal diameter greater than 3 mm read 15-20 minutes after the test compared to the initial wheal size) [18].
The very limited usefulness of skin testing with penicilloyl-polylysine and the minor determinant mixture in evaluating nonimmediate reactions to penicillins.
Hem ENDA hem de Amerika Alerji Astim Immunoloji Akademisi beta laktamlarla olusan hizli reaksiyonlann tanisinda penicilloyl-polylysine (PPL) ve minor determinant kansimi (MDM) ile deri prik testinin ilk sirada oldugunu belirtmektedirler (32).
Evaluation of penicillin hypersensitivity: value of clinical history and skin testing with penicilloyl-polylysine and penicillin G.
Brown BC, Price EV, Moore MB: Penicilloyl-polylysine as an intradermal test of penicillin sensitivity.