penetrating keratoplasty

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Related to penetrating keratoplasty: Penetrating keratoplasty surgery

pen·e·trat·ing ker·a·to·plas·ty

corneal transplant with replacement of all layers of the cornea, but retaining the peripheral cornea.


Excision of corneal tissue and its replacement by a cornea from a human donor. This can be done either over the entire cornea (total keratoplasty) or over a portion of it (partial keratoplasty). Two main techniques are used: (1) the penetrating keratoplasty in which the entire thickness of the cornea is removed and replaced by transparent corneal tissue; (2) the lamellar keratoplasty in which a superficial layer is removed and replaced by healthy tissue. Common indications to perform keratoplasty are therapeutic (e.g. keratoconus, corneal ulcer) or cosmetic (e.g. removing an unsightly opacity). Syn. corneal transplant. See ciclosporin; granular dystrophy; eye bank; corneal graft; immunosuppressants.


plastic surgery of the cornea; corneal grafting.

lamellar keratoplasty
a partial thickness graft of the cornea; only epithelium and superficial stroma is removed and replaced by donor tissue as distinct from penetrating or full-thickness grafting.
optic keratoplasty
transplantation of corneal material to replace scar tissue that interferes with vision.
penetrating keratoplasty
a full thickness of the cornea is removed and replaced with donor tissue.
tectonic keratoplasty
transplantation of corneal material to replace tissue that has been lost.
References in periodicals archive ?
In addition to LASIK, the IntraLase technology is used to create incisions for lamellar keratoplasty, penetrating keratoplasty, intrastromal ring implants and for the preparation of the donor tissue used in corneal transplants.
It is far more preferable to perform lamellar surgery and only remove the diseased area rather than a penetrating keratoplasty to remove the entire cornea.
Although the risks of CXL have not yet been fully quantified, the potential for some risk would seem justified in the context of a progressive disease that is otherwise likely to result in further impairment of VA, or even the need for lamellar or penetrating keratoplasty.
IntraLase received FDA 501K clearance for use of the IntraLase FS30 laser in creating the corneal resections performed in lamellar keratoplasty and penetrating keratoplasty procedures, allowing IntraLase to develop further therapeutic applications.