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Mortar & pestle sign Rheumatology A descriptor for marked resorption of distal phalanges–acroosteolysis, a radiologic finding typical of scleroderma DiffDx Severe burns with soft tissue contracture, 'black toe' disease–ainhum, hyperparathyroidism, neural leprosy, SLE, neuropathies–eg, DM, tabes dorsalis, progeria, psoriatic arthritis, PVC exposure, Reiter syndrome, rheumatoid arthritis, sarcoidosis. Cf Spade deformity.