pegylated


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pegylated

(peg'i-lāt-ed),
Substance with chemically attached glycol moieties.
[PEG (polyethylene glycol) + -yl, chemical suffix, + -ated, pp. suffix]

pegylated

or

PEGylated

(pĕg′ə-lā′tĭd)
adj.
Covalently attached to polyethylene glycol, as in certain drugs.
References in periodicals archive ?
Biopharmaceutical company Eiger BioPharmaceuticals Inc (Nasdaq:EIGR) revealed on Thursday the receipt of the US Food and Drug Administration's (FDA) Fast Track designation for pegylated interferon lambda 1a (Lambda) as a potential treatment for chronic hepatitis delta virus (HDV) infection.
The addition of boceprevir to pegylated interferon and ribavirin increased the chance of a SVR (63-66% in treatment-naive patients and 52-75% in previously treated patients), (4,5) but it also was associated with an increased incidence of adverse events during treatment, especially anemia and dysgeusia.
Simeprevir is an NS3/4A protease inhibitor jointly developed by Janssen R&D Ireland and Medivir and indicated for the treatment chronic hepatitis C infection in combination with pegylated interferon and ribavirin in adults with compensated liver disease (including cirrhosis) who are treatment naive or who have failed previous interferon therapy (pegylated or non-pegylated) with or without ribavirin.
presented interim results from EUROP (Evaluation of Pegylated Interferon (Unipeg(r)) for Response in Pakistani Population) Clinical Trial Study last year at EASL Prague, Czech Republic, September 14-16, 2012.
Loss of the hepatitis B e antigen (HBeAg) and hepatitis B viral (HBV) DNA levels below 200 IU / mL after 48 weeks of therapy occurred in 18% of patients randomized to entecavir (Baraclude) and pegylated interferon alfa-2a (Pegasys), vs.
In three phase III studies of more than 2,000 treatment-naive and treatment-experienced patients, the addition of telaprevir, an HCV-specific protease inhibitor taken three times a day for up to 12 weeks, to pegylated interferon and ribavirin significantly increased the sustained virologic response (SVR) rate, compared with pegylated interferon and ribavirin therapy.
A message was sent to Getz at the launching of Pegylated Interferon production in Pakistan by the minister who was supposed to attend the ceremony but was held back because urgent issues related to floods were to be managed.
KARACHI, August 07, 2010 (Balochistan Times): The inauguration ceremony of local biotech production of Pegylated Interferon Alfa 2-a was held at Getz Pharma here on Saturday.
Existing PEGylation technologies produce products that are PEGylated at multiple sites, which can result in heterogeneous population of PEGylated molecules and a decrease in potency compared to the un-PEGylated analogue.
In step 1, people with HCV and HIV started anti-HCV therapy consisting of pegylated interferon plus a ribavirin dose based on weight: 1.