The disks contained the following antibiotics: 10 [micro]g ampicillin, 30 [micro]g cephalothin, 30 [micro]g cefotaxime, 30 ug ceftazidime, 30 [micro]g cefuroxime, 1 [micro]g dicloxacillin, 15 [micro]g erythromycin, 10 [micro]g gentamicin, 5 [micro]g pefloxacin
, 10 IU penicillin, 30 [micro]g tetracycline, and 25 [micro]g trimethoprimsulfamethoxazole.
Orbifloxacin, danofloxacin, pipemidic acid, mathofloxacin, lomefloxacin, pefloxacin, enrofloxacin, norfloxacin, ciprofloxacin, and ofloxacin were purchased from Sigma (St.
Other (fluoro)quinolones (marbofloxacin, pipemidic acid, danofloxacin, and orbifloxacin) were detected only in the S-w wastewater sample, whereas pefloxacin was found in S-w and [F.
GBS CNR0717, a capsular serotype IV strain, was suspected to have reduced susceptibility to FQs because no inhibition zone was observed around disks containing norfloxacin and pefloxacin disks, and reduced diameters were observed around disks containing ciprofloxacin and levofloxacin.
There is also a molecule-dependent target specificity: mutations in parC are generally selected by pefloxacin, ciprofloxacin, and levofloxacin, and those in gyrA are selected by sparfloxacin, gatifloxacin, moxifloxacin, gemifloxacin, and garenoxacin (5).
Birds of groups II and III received ciprofloxacin and pefloxacin
by the same route at the rate of 10 and 12 mg/kg body weight, respectively, every day for a similar period.
1999) examined these norfloxacin resistant clinical isolates, it was shown that the strains also have increased resistance to trovafloxacin, ciprofloxacin, levofloxacin, sparfloxacin and pefloxacin
Of 98 cases in the literature, 37% were associated with pefloxacin
(400-800 mg daily, mean duration of 18 days), and 26% were associated with ciprofloxacin (500-2,000 mg daily, mean of 24 days).
During this prolonged episode, the patient was administered several types of medication, including tramadol, propacetamol, enoxaparin, digoxin, amiodarone, furosemide, atenolol, cefuroxime, netilmicin, cefazolin, pefloxacin
, metronidazole, ondansetron, alizapride, pantoprazole, haloperidol, and diazepam.
Other isolates were resistant to penicillin, lincomycin, erythromycin, pristinamycin, kanamycin, pefloxacin
(Armand-Lefevre et al.
Analysis of the antimicrobial-susceptibility profile of these strains showed that two were resistant to at least one macrolide antimicrobial agent, four were resistant to aminoglycosides, and four were resistant to pefloxacin
Susceptibility was conserved for tetracycline, ampicillin, cephalotin, and pefloxacin