pediatric autoimmune neuropsychiatric disorder

pediatric autoimmune neuropsychiatric disorder associated with streptococci

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PANDAS

Any of the childhood behavioral disorders (esp. tic disorders, Tourette's syndrome, and obsessive-compulsive disorder) that begin before puberty and are associated with and worsened by group A beta-hemolytic streptococcal infections (e.g., strep throat or scarlet fever). Researchers suspect that an autoimmune response to the infection is responsible for the syndrome.
References in periodicals archive ?
PANDAS: Pediatric autoimmune neuropsychiatric disorder associated with group A streptococci, www.
Prospective identification and treatment of children with pediatric autoimmune neuropsychiatric disorder associated with group A streptococcal infection (PANDAS).
Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: clinical description of the first 50 cases.
Prevalence of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection by history in a consecutive series of community referred children evaluated for tics.
Specific disorders covered include Tourette's syndrome, bipolar disorder, executive dysfunction, obsessive compulsive disorder, ADHD, memory deficits and slow processing speed, nonverbal learning disability, pervasive developmental disorders, Asperger's syndrome, anxiety disorders, depression, sensory processing disorder, pediatric autoimmune neuropsychiatric disorder associated with strep (PANDAS), storms or rages, oppositional defiant disorder, and sleep problems.
Pediatric autoimmune neuropsychiatric disorder associated with streptococcus (PANDAS) refers to when children with streptococcal infections as well as OCD and/or a tic disorder experience prepubertal symptom onset, sudden onset or abrupt exacerbations, association with neurological abnormalities during exacerbations (adventitious movements or motoric hyperactivity), and temporal association between exacerbations and infections.
The list of diagnoses for her condition is long: fibromyalgia, autoimmune disease, chronic fatigue syndrome, celiac disease, chronic infection, allergies, short-lasting unilateral neuralgiform headache with conjunctival injection and tearing syndrome, Raynaud's phenomenon, pediatric autoimmune neuropsychiatric disorders associated with streptococcal, gastrointestinal reflux disease, irritable bowel syndrome.
But enough evidence exists to suggest a link between acute strep infections and the onset of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS), said Dr.
Pediatric autoimmune neuropsychiatric disorders associate with streptococcal infections: the first 50 cases.
Researchers call such cases PANDAS, an acronym for pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections.
Some researchers suspect the body's natural response to infection -- the production of certain antibodies directed to parts of the brain -- might be linked in some way to pediatric autoimmune neuropsychiatric disorders (PANDAS), including TS, OCD, and tic disorder.
The ongoing pilot study has randomized 18 children with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) to prophylaxis with either azithromycin or penicillin.

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