peanut allergy


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peanut allergy

Immunology A common cause of anaphylactic reactions which, unlike some allergies, is rarely outgrown; PA is the most common cause of food allergy in the US, and a leading cause of food-induced anaphylaxis and death after accidental exposure

peanut allergy

An IgE-mediated immediate hypersensitivity reaction to the consumption of peanuts (the seeds of Arachis hypogaea). Peanut allergens are designated Ara by the World Health Organization. Peanut allergy is the most important food allergy in the U.S., affecting more than a million people. Reactions range from mild (rashes) to life-threatening (closure of the airway, cardiac dysrhythmias, coma). About 50 people die of peanut allergy in the U.S. each year.

Patient care

People with known allergies to peanuts must avoid eating raw or processed peanuts and also products containing or prepared with peanut oil . Those affected by peanut allergy should learn to watch for the signs of anaphylaxis (hives, pruritus, rashes in the skin creases, shortness of breath, choking, wheezing, stridor). People with known anaphylaxis to peanuts should carry epinephrine injectors and use them at the onset of a hypersensitivity reaction. (Repeated use may be necessary in persistent reactions.) Cross-reactivity to other legumes (peas, soy products) may affect some people and pose important health risks. Affected people should wear medical alert bracelets or necklaces identifying their condition. Densensitization can be accomplished with modified peanut allergens.

See also: allergy

peanut allergy

An often severe form of ALLERGY in which up to one-third of sufferers experience ANAPHYLAXIS. Peanut allergy is not more common than other food allergies, all of which are rare, affecting about 1 person in 100,000 per year. It is becoming commoner, however, and is liable to be more severe than most, and is especially dangerous in asthmatic children. Peanut proteins may be found in such diverse foodstuffs as chocolate spread and scotch eggs. The allergy has been shown to be significantly associated with intake of soy milk or soy formula and with the use of skin preparations containing peanut oil. The increasing incidence is thought to be due to unduly early exposure of babies to peanut butter after weaning.
References in periodicals archive ?
The new diagnostic test, which accurately discriminates peanut allergy from tolerance, will mean we can target avoidance to those patients really at risk and remove the considerable stress that comes from the many false positive sensitivity tests," he added.
With commercial availability of the uKnow Peanut Test, we expect that many patients who were previously diagnosed with peanut allergy will now be given additional information at the molecular level to better assess their lifestyle and management choices.
Exposure was compared in three groups of children of the same age: Children with peanut allergy, children with egg allergy but not peanut sensitized and non-allergic children.
We believe that our ISS-based peanut allergy immunotherapeutic addresses the major challenge in treating this deadly allergy, namely, the ability to mask presentation of the allergen and promote a Th1 response, thus effectively transforming the allergen into a drug," said Dino Dina, MD, president and chief executive officer of Dynavax.
Food allergies are a very common life-limiting condition, especially in children, and cause hundreds of fatalities every year, so the development of an oral vaccine to treat peanut allergy has the potential to change thousands of lives all over the world.
Randomized trial of peanut consumption in infants at risk for peanut allergy.
Among the 530 children who had no signs of peanut allergy (on a skin-prick test) when they entered the study, 14 percent of those who avoided peanut butter--but just 2 percent of those who ate peanut butter--were allergic by age five.
Pediatric allergist Gideon Lack of King's College London and his team enrolled babies ages 4 to 11 months who were deemed at elevated risk of peanut allergy because they either had severe eczema or were allergic to eggs.
An exciting new trial showing you can slash the risk of peanut allergy by exposing babies as young as four months to peanuts comes as no shock to me.
TEHRAN (FNA)- Introduction of peanut products into the diets of infants at high risk of developing peanut allergy was safe and led to an 81 percent reduction in the subsequent development of the allergy, based on a clinical trial.
The best way to prevent a peanut allergy in young children is to feed them peanut products, Irish Times reports referring to a study published on Monday.
For years, parents of babies who seem likely to develop a peanut allergy have gone to extremes to keep them away from peanut-based foods.