Intrommune's lead product, INT301, is expected to be a safe, effective and convenient therapy for patients who suffer from peanut allergy
. There is no FDA-approved treatment for peanut allergy
or any other food allergy.
Researchers suggest that in order to prevent peanut allergy
, peanut protein (such as peanut butter or powdered puff) may be introduced at home for most babies between 4 and 6 months as one of the first foods.
Gupta also showed that peanut allergy
was reported most often among white children (47.7%) and children from households with an annual income of $50,000-$99,999 (41.7%).
is persistent in the majority of cases, and only outgrown in ~20% of patients.
"Until recently there has been nothing to offer peanut allergy
suffers other than education around avoidance and self-treatment of reactions."
Reportedly, ASIT biotech now has three product candidates selected on the ASIT+ platform for allergies with the highest prevalences, namely allergic rhinitis caused by grass pollen, peanut allergy
and house dust mite allergy.
A randomized, controlled trial (Learning Early About Peanut Allergy
; LEAP, published in 2015) demonstrated that early introduction of peanut-containing food (ie, at 4 months to < 11 months of age) in infants at high risk for peanut allergy
(defined as presence of severe atopic dermatitis, egg allergy, or both) resulted in a significantly lower risk of developing peanut allergy
by age 60 months compared with peanut avoidance.
THE RESULTS: Children who avoided peanut containing foods had a much higher incidence of having a peanut allergy
compared to children who had consistently and frequently consumed peanut products from a young age.
Previous guidelines published in 2010 did not provide specific treatment strategies for peanut allergies because of a lack of research, but the significant results of the Learning Early About Peanut Allergy
(LEAP) study suggested that early exposure to peanut-containing foods reduces the risk of developing allergies.
Global Markets Direct's, 'Peanut Allergy
- Pipeline Review, H1 2016', provides an overview of the Peanut Allergy
The increase in allergy to peanut in westernised countries  has sparked widespread interest in peanut allergy
. Recent progress has been made in identifying risk factors for peanut allergy
, such as epithelial barrier defects leading to epicutaneous sensitisation by peanut protein.