pattern recognition receptor


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Related to pattern recognition receptor: Natural killer cells, Toll like receptor

pattern recognition receptor

Abbreviation: PRR
A receptor on an antigen-presenting cell of the immune system that recognizes molecular sequences found on disease-causing organisms but not host cells. PRRs detect the presence of pathogen-associated chemicals such as lipopolysaccharides, mannans, and teichoic acids.
See also: receptor
References in periodicals archive ?
Acknowledging the enormous expansion of this field as researchers have identified high resolution structures of pattern recognition receptors, contributors detail how cells sense signals to activate the innate immune response.
Appropriate areas of research include, but are not limited to: 1) Characterization of host cells involved in the innate immune response to protozoa; 2) Identification of novel pathogen-associated molecular pattern recognition receptors on host cells; 3) Characterization of mediators of innate immunity that are produced by host cells stimulated by protozoa; 4) Elucidation of the intracellular signaling pathways in the mammalian innate immune cells that are stimulated by protozoa; 5) Comparison of human versus animal model molecular responses to protozoan pathogens or their components; 6) Human or animal model gene mutations or polymorphisms associated with distinctive innate immune responses to protozoa.
Innate Pharma SA, the innate immunity company developing first-in-class drugs for cancer and inflammatory diseases, announces today that new preclinical data for two proprietary programs were presented at the Molecular Pattern Recognition Receptors meeting and the American Association for Cancer Research ( CR ) annual meeting:

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