pathotype

pathotype

(păth′ō-tīp) [Gr. pathos, disease, + typos, type]
A disease-causing variant of a microorganism. It is distinguishable from other members of its species by its virulence and by unique molecular markers.
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References in periodicals archive ?
All morphological properties were consistent with those pre-viously described for pathotype A by Sun et al.
In order to determine the pathotype of each isolate, a set of 12 differential cultivars consisting of six Andean (DonTimoteo, G 11796, Bolon Bayo, Montcalm, Amendoin, G 5686) and six Mesoamerica (Pan 72, G 2858, Flor deMayo, Mexico 54, BAT 332, Cornell 49-242) cultivars were used.
Finally, O80 EHEC appears to be a hybrid pathotype that combines intestinal VFs (Shiga toxin [stx], intimin [eae], enterohemolysin [ehxA]) and extraintestinal VFs (aerobactin [iucC]; salmochelin [iroN], an iron uptake protein encoded by sitABCD; serum resistance protein [issp]; a putative secretion system I [etsC]; omptin [ompTp]; hemolysin [hlyF], and 2 bacteriocins [cia and cva]), suggesting the presence of a pS88-like plasmid (11).
The distribution of 42 DEC pathotype isolates were: EPEC was found in 19 (45.3%), EAEC in 17(40.5%), ETEC in 3 (7.1%), EIEC in 3 (7.1%) and 0 (0%) in STEC and controls.
However, strains of this pathotype appear to circulate as a part of the gut flora with ruminants such as cattle, sheep and goats serving as the major animal reservoirs (Horcajo et al., 2010; Oporto et al., 2008).
Most of the strains isolated from outbreaks of haemorrhagic colitis and haemolytic uraemic syndrome, and those infections with more severe symptoms, typically express both Stx and intimin along with carriage of pO157 (30, 31, 36), and are usually designated as the pathotype enterohaemorrhagic E.
Newcastle disease virus (NDV) can be grouped into five pathotypes with respect to tissue tropism and clinical signs, that is to say, (a) viscerotropic velogenic pathotype and (b) neurotropic velogenic pathotype.
For many years, our workgroup has participated in the surveillance of acute diarrheal disease in Uruguayan children [13-16], and we confirmed that EPEC is the most prevalent DEC pathotype locally.