pathognomonic


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pathognomonic

 [path″og-no-mon´ik]
specifically distinctive or characteristic of a disease or pathologic condition; denoting a sign or symptom on which a diagnosis can be made.

path·og·no·mon·ic

(path'og-nō-mon'ik),
Characteristic or indicative of a disease; denoting especially one or more typical symptoms, findings, or pattern of abnormalities specific for a given disease and not found in any other condition.
[see pathognomy]

pathognomonic

(pə-thŏg′nə-mŏn′ĭk, păth′əg-nō-)
adj.
Specific to a certain disease or condition, as a symptom or finding on physical examination.

pathognomonic

Medtalk adjective Referring to a distinctive sign, Sx, or characteristic of a disorder on which a diagnosis is made

path·og·no·mon·ic

(path'og-nō-mon'ik)
Denoting something characteristic or indicative of a disease; denoting especially one or more typical symptoms, findings, or patterns of abnormalities specific to a given disease and not found in any other condition.

pathognomonic

Of a symptom or physical sign that is so uniquely characteristic of a particular disease as to establish the diagnosis.

path·og·no·mon·ic

(path'og-nō-mon'ik)
Characteristic or indicative of a given disease; denoting especially one or more typical symp toms, findings, or pattern of abnormalities specific for a given disease and not any others.
References in periodicals archive ?
* "Jelly" (mucinous ascitic fluid) in the belly is pathognomonic of pseudomyxoma peritonei.
Typically, the diagnosis is delayed until the appearance of trichorrhexis invaginata which is pathognomonic. Therefore, hair examination by trichoscopy or trichogram should be carried out early so that the diagnosis would not have been missed or delayed.
The low incidence and lack of pathognomonic features of epiploic appendagitis make it an easily missed diagnosis.
The presence of hooklets on a necrotic and degenerated background was considered as pathognomonic for diagnosis of HD (Figure 1).
Immunocytochemistry shows foamy histiocytes with positive stain for CD68, which is pathognomonic for non-Langerhans cell histiocytes.
In addition to the diagnostic dilemma of rather unspecific appearance on endoscopy and eventually vague clinical symptoms as outlined above, the pathognomonic features of epithelioid granulomas with Langhans giant cells, central caseous necrosis, and presence of acid-fast bacilli are identified only in a minority of biopsy specimens [12, 13].
Emperipolesis within the histiocyte cytoplasm is a pathognomonic finding [2-4].
Histopathologic evaluation of skin affected by GVHD shows a lichenoid tissue reaction, but this is not pathognomonic. Further evaluation with FISH analysis and genetic chimerism analysis of peripheral blood confirms the diagnosis.
We diagnosed this patient with vitamin C deficiency (scurvy) based on the fact that she had perifollicular hemorrhages with corkscrew hairs, which is a pathognomonic feature of the deficiency.
If the phenotype is pathognomonic, Sanger sequencing is preferred for confirmation.
Conversely, the presence of SUAC is generally considered pathognomonic for TYR1.
Biett's collarette is a pathognomonic sign for secondary syphilis.