pathogenicity island


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pathogenicity island (PAI)

a large gene cluster (‘island’), normally found on the CHROMOSOME of a pathogenic BACTERIUM, that specifies functions associated with VIRULENCE, for example production of TOXINS, ADHESINS. The cluster may be able to transpose to other REPLICONS, for example PLASMIDS, and be transferred in nature by HORIZONTAL GENE TRANSFER.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
Typical and atypical EPEC seem to constitute two groups of distinct organisms that have in common the LEE pathogenicity island. Atypical EPEC are closer to STEC in genetic characteristics, serotypes, production of toxins, reservoir, and other epidemiologic aspects.
Interplay between pathogenicity island carriage, resistance profile and plasmid acquisition in uropathogenic Escherichia coli.
coli pathotypes have emerged overtime through the transfer of virulence factors from other bacterial species by way of mobile genetic elements such as pathogenicity islands, transposons, and plasmids (7).
E.coli have many virulence factors, including adhesin, enterotoxin, shiga toxigenic and pathogenicity island which is widely distributed among diarrheic pigs (Zhang et al., 2007; Contrepois et al., 1989).
"A Novel Putative Enterococcal Pathogenicity Island Linked to the esp Virulence Gene of Enterococcus faecium and Associated with Epidemicity." Journal of Bacteriology, 186(3): 672-682.
Some studies have associated several virulence genes with the APEC pathotype, and these genes maybe present on plasmids or chromosomal DNA fragments called PAIs (pathogenicity islands) [6-10].
These features suggest that this DNA fragment is a horizontally acquired transposon-like element (9) and together with the frequent association of the usp gene with UPEC strains, imply that this DNA fragment could be the previously unrecognized pathogenicity island (PAI) of UPEC.
A bacteriophage encoding a pathogenicity island, a type-IV pilus and a pahage receptor in cholera bacteria.
The Salmonella Pathogenicity Island (SPI) 1 contributes more than SPI2 to the colonization of the chicken by Salmonella enterica serovar Typhimurium BMC Microbiology 9:3 Disponible en: http://www biomed central com/1471-2180/9/3
The pathogenicity island studied is a prototype of a new family of virulent DNA recently discovered which also can be transferred to other species of bacteria such as Listeria monocytogenes, responsible for a large number of intoxications.