Loss of imprinting of a paternally
expressed transcript, with antisense orientation to KVLQT1, occurs frequently in Beckwith-Wiedemann syndrome and is independent of insulin-like growth factor II imprinting.
Discrimination of complete hydatidiform mole from its mimics by immunohistochemistry of the paternally
imprinted gene product p57KIP2.
The human GNAS1 gene is imprinted and encodes distinct paternally
and biallelically expressed G proteins.
Brannan, "The Prader-Willi syndrome imprinting center activates the paternally
expressed murine Ube3a antisense transcript but represses paternal Ube3a," Genomics, vol.
2009: Molecular phylogenetics of the bat genus Scotophilus (Chiroptera: Vespertilionidae): perspectives from paternally
and maternally inherited genomes.
Mammals never develop to term without the cooperation of both of the parental genomes: embryos with either two maternally or paternally
derived genomes, such as parthenogenetic or androgenetic embryos, exhibit early embryonic lethality (Fig.
Their sensibilities combine so well: Clark quick and smart, his letters animated with filial devotion; Berenson slow and contemplative, often florid, delighting in highly obscure allusions, and paternally
Molecular analysis of cffDNA in maternal plasma has emerged since 1997 for prenatal diagnosis like fetal RHD genotyping, fetal sexing for X-linked disorders (1), paternally
inherited genetic diseases and pregnancy-associated conditions such as preeclampsia (2).
Because p57KIP2 is paternally
imprinted, and both the X chromosomes in complete moles are derived from the father, it is expected that reduced or absent expression of p57KIP2 protein is seen in complete moles.12
[p57.sup.kip2], a paternally
imprinted and maternally expressed gene protein which shows reduced or absent expression in cytotrophoblast and villous mesenchymal cells of complete mole, and strongly expressed in those of partial mole.
As part of the agreement, Sequenom is now the owner of global intellectual property for noninvasive prenatal genetic diagnostic testing on paternally
inherited fetal nucleic acids derived from maternal plasma or serum.
The certificate reads: "His Holiness John Paul II paternally
imparts a special Apostolic Blessing to A Wilf Mannion as a pledge of continued divine protection."