Johan von Heijne, president and CEO of Biolin Scientific states, This deal affirms our commitment to invest in high-throughput screening using automated patch clamping
, and our intent to vigorously protect our broad range of innovations and intellectual property rights.
Forest is working to automate the technology used in patch clamping
in order to more effectively gather data from many neurons at the same time, improving both efficiency and the quality of data collected.
Kodandaramaiah, Boyden and Forest set out to automate a 30-year-old technique known as whole-cell patch clamping
, which involves bringing a tiny hollow glass pipette in contact with the cell membrane of a neuron, then opening up a small pore in the membrane to record the electrical activity within the cell.
Other chapters address visual physiology, mechanosensation, chemosensory coding, patch clamping
, and olfactory and visually guided behavior and conditioning to study learning and memory, social behaviors of aggression and courtship, circadian rhythm, and feeding.
Molecular Devices acquired Cytion SA, which develops systems for analyzing ions through automated patch clamping
, for $7.
Using patch clamping
-- a technique for measuring the flow of charged particles, or ions, in and out of cells -- researchers from Washington University in St.
The 48-channel QPatch HTX takes automated patch clamping
to an even higher level.
This novel technology provides researchers with the means to dynamically study excitation dependent cellular responses without the requirement for a direct physical link to the cell (such as with electrodes in patch clamping
or transistor contact necessary in micro electrode arrays).
is the gold standard for screening ion channels in drug discovery.
This technology provides researchers with the means to dynamically study excitation dependent cellular responses without the requirement for a direct physical link to the cell (such as with electrodes used for patch clamping
or transistor contact necessary for use with micro electrode arrays).
Applications for the MK26 Vibration Isolation Workstation include fluorescent dye imaging, patch clamping
, scanning probe microscopes, microhardness testing, sensor calibration, profilers, and interferometers in fields such as biology, semiconductor processing, materials research, aerospace engineering, and medical research.
It is claimed to be taking automated patch clamping
to a new and even more powerful level.