First, biocompatibility of implanted devices will be assessed using in vivo patch clamping
of spinal motoneurons in healthy fish implanted with nanodevices.
Kodandaramaiah, Boyden and Forest set out to automate a 30-year-old technique known as whole-cell patch clamping
, which involves bringing a tiny hollow glass pipette in contact with the cell membrane of a neuron, then opening up a small pore in the membrane to record the electrical activity within the cell.
Swedish biotechnology instruments firm Biolin Scientific (STO:BLIN), owned by private equity firm Ratos, said today it would buy Danish automated patch clamping
(APC) solutions provider Sophion Bioscience for DKK145m (USD28m/EUR19.
The total sales price for Sophion Bioscience, which specialises in products and integrated solutions for automated patch clamping
in living cells, is DKK155m.
Other chapters address visual physiology, mechanosensation, chemosensory coding, patch clamping
, and olfactory and visually guided behavior and conditioning to study learning and memory, social behaviors of aggression and courtship, circadian rhythm, and feeding.
Molecular Devices acquired Cytion SA, which develops systems for analyzing ions through automated patch clamping
, for $7.
Using patch clamping
-- a technique for measuring the flow of charged particles, or ions, in and out of cells -- researchers from Washington University in St.
Johan von Heijne, president and CEO of Biolin Scientific states, This deal affirms our commitment to invest in high-throughput screening using automated patch clamping
, and our intent to vigorously protect our broad range of innovations and intellectual property rights.