passive cutaneous anaphylaxis test

pas·sive cu·ta·ne·ous an·a·phy·lax·is test

an animal is injected intradermally with antibody (usually IgE) and subsequently challenged intravenously with a mixture of antigen and Evans blue dye 24-48 hours later. A dark blue area indicates a positive reaction due to the leakage of the dye at the site of antigen-antibody reactions.
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Anti-allergic activity of CXT was evaluated by passive cutaneous anaphylaxis test (PCA); acetic acid-induced writhing tests were used to evaluate the analgesic effects of CXT; acetic acid-induced vascular permeability tests were performed to evaluate anti-inflammatory effect of CXT.
Anti-allergic activity of CXT was evaluated by passive cutaneous anaphylaxis test (PCA); acetic acid-induced writhing test was used to evaluate the analgesic effect of CXT ; acetic acid-induced vascular permeability test was performed to evaluate the anti-inflammatory effect of CXT.
To confirm that IgE is the responsible isotype inducing the allergic symptoms, passive cutaneous anaphylaxis tests were performed in naive animals.
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