Immunohistochemically, they are also positive for markers of proximal convoluted tubule (PCT) (CD10, carbonic anhydrase IX, vimentin, AMACR) as well as distal tubule/collecting duct (CK7, CK19, parvalbumin
Paired-pulse facilitation at recurrent Purkinje neuron synapses is independent of calbindin and parvalbumin
during high-frequency activation.
These entities can also be positive for PAX2, kidney-specific cadherin, carbonic anhydrase IX, and parvalbumin
Other proteins such as calretinin, calbindin, and parvalbumin
function as localized calcium buffers, especially in the pre- and postsynaptic regions, regulating Ca2+ densities to affect the sensitivity of the neuron to various stresses such as oxidative damage, ischemia, and depolarization.
Conversely, activation of these parvalbumin
interneurons significantly reduces fear responses in rodents.
Previous studies have proposed the primary pathway is a parvalbumin
positive pathway and the diffuse pathway is calbindin positive.
University researchers were able to pinpoint a specific protein, parvalbumin
- which aids in high-speed relaxation of fast twitching muscles in nature - and optimize it to become a calcium sponge for heart muscle.
Several markers are available for these diagnostic goals, including the renal cell carcinoma marker antigen (RCCM), kidney-specific cadherin, cytokeratin subtypes, CD10, vimentin, alpha-methylacyl coenzyme A racemase, parvalbumin
, and carbonic anhydrase IX.
Functional characterization of parvalbumin
from the Arctic cod (Boreogadus saida): similarity in calcium affinity among parvalbumins
from polar teleosts.
One possible reason for this difference is that calretinin and parvalbumin
expression might be regulated at the translational level after blast exposures, which needs to be investigated further.
A recombinant hypoallergenic parvalbumin
mutant for immunotherapy of IgE-mediated fish allergy.
The expression of parvalbumin
is relatively low in both the central and the basomedial nuclei of the amygdala; the expression of calretinin and calbindin, however, shows some variation between these nuclei.