parvalbumin


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par·val·bu·min

(par'val-byū'min), [MIM*168890]
Any of a group of small water-soluble calcium-binding proteins distinct from calmodulin and other calcium-binding proteins; found in the brain, skeletal muscle, and retina, but not in the heart, liver, or spleen, of various species.
[L. parvus, small, + albumin]

parvalbumin

A small, stable, water-soluble calcium-binding protein with three EF-hand-type-binding domains.
References in periodicals archive ?
Scientists already knew that the Atlantic toadfish produces large amounts of a protein called parvalbumin that basically cleans up the ions from the release site but this clean up still happens when the fish shuts up.
20] Our study found a decrease in GABA concentration in the anterior cingulate cortex; therefore, the GABA- glutamate hypothesis speculated that Fast-spiking parvalbumin positive interneurons released less GABA in the course of schizophrenia.
Calcium-binding protein (calbindin-D28K) and parvalbumin immunocytochemistry in the normal and epileptic human hippocampus.
The genes for the highly homologous Ca 2+-binding proteins on-comodulin and parvalbumin are not linked in the human genome.
Reductions have been found in the PFC parvalbumin of adolescent separated subjects.
m and use as a neurotransmitter GABA, associated with the parvalbumin in more than 60% of the neurons.
Quantitative distribution of parvalbumin, calretinin, and calbindin D-28k immunoreactive neurons in the visual cortex of normal and Alzheimer cases.
Parvalbumin is constantly expressed in chromophobe renal carcinoma.
Proteomic analysis in animals C57BL/6-resistant and DBA/2 sensitive, following 12-O-tetradecanoylphorbol-13-acetate (TPA) administration, demonstrated 19 different expressed proteins, such as S100 calcium binding proteins A8, A9, and A11 as well as parvalbumin a and annexin A1 [49].
In their brains, a particular group of nerve cells called parvalbumin interneurons didn't mature normally.
Immunohistochemically, they are also positive for markers of proximal convoluted tubule (PCT) (CD10, carbonic anhydrase IX, vimentin, AMACR) as well as distal tubule/collecting duct (CK7, CK19, parvalbumin, BerEp4).
Paired-pulse facilitation at recurrent Purkinje neuron synapses is independent of calbindin and parvalbumin during high-frequency activation.