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A natural sesquiterpene lactone found in feverfew (Tanacetum parthenium), which has a variety of in vitro activities:
• Inhibition of serotonin and prostaglandins, which may explain feverfew’s efficacy in treating migraines;
• Induces apoptosis, killing the stem cells that give rise to acute myeloid leukaemia;
• Blocks Leishmania amazonensis;
• Interferes with microtubule activity;
• Anti-inflamatory; and