paroxetine


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paroxetine

 [pah-rok´sĕ-tēn]
a selective serotonin reuptake inhibitor administered orally as the hydrochloride salt as an antidepressant and to treat obsessive-compulsive, panic, and social anxiety disorders.

paroxetine

/par·ox·e·tine/ (pah-rok´sĕ-tēn) a selective serotonin uptake inhibitor used as the hydrochloride salt to treat depression and obsessive-compulsive, panic, and social anxiety disorders.

paroxetine

(pă-rŏk′sĭ-tēn′)
n.
A drug of the SSRI class, C19H20FNO3, used in its hydrochloride form to treat depression, anxiety, and certain other disorders, including obsessive-compulsive disorder.

paroxetine

a selective serotonin reuptake inhibitor.
indications It is prescribed in the treatment of mental depression, obsessive-compulsive disorder, panic disorders, and anxiety disorders, including social anxiety and general anxiety. Unlabeled uses include treatment of impulse control disorders, premenstrual syndrome, and vasomotor symptoms of menopause.
contraindications It should not be given to patients taking monoamine oxidase inhibitors. Caution is advised in administering the drug to patients with a history of drug abuse, mania, seizures, suicidal tendencies, or kidney or liver disease.
adverse effects The side effects most often reported include decreased libido and ejaculatory disturbances, nausea, diarrhea, vomiting, constipation, abdominal pain, flatulence, changes in appetite, and muscle weakness. Paroxetine may also cause SIADH and/or hyponatremia and lead to or exacerbate coagulation disturbances because of impairment of platelet aggregation.

paroxetine

A SEROTONIN RE-UPTAKE INHIBITOR drug. A brand name is Seroxat.

paroxetine,

n brand name: Paxil;
drug class: antidepressant;
action: selectively inhibits the uptake of serotonin in the brain;
use: depression.
References in periodicals archive ?
The changes in morphology of isolated stem cell and neurogenic induced cells were analyzed following the Paroxetine exposure for 2, 4 and 6 days.
Results: The percent responses with acetylcholine, serotonin and paroxetine were 100, 158.
Before that litigation went to trial, GUK and Alpharma each entered into agreements with GSK, which included terms prohibiting their independent entry into the UK paroxetine market.
and his colleagues concluded that paroxetine "is generally well tolerated and effective for major depression in adolescents" (J Am Acad Child Adolesc Psychiatry.
High posterior odds ratios were observed for five birth defects with paroxetine use: anencephaly (3.
The goal was to determine whether or not generic duloxetine was similar in effectiveness and safety to paroxetine in the treatment of MDD--that is, it is a 'non-inferiority' trial.
Therefore, the market size of paroxetine is expected to expand in the next few years in China.
Although these events are generally self-limiting, there have been reports of serious discontinuation symptoms with other formulations of paroxetine.
While the newly approved version of paroxetine helps avoid weight gain and sexual dysfunction typically caused by higher doses of antidepressants, there are certain groups of patients who are not candidates for this alternative hot flash treatment, explains Dr.
Our hypothesis was that individuals with higher aerobic capacities are less responsive to pharmacological activation of the serotonergic system and would, therefore, exhibit no changes on exercise performance induced by the ingestion of paroxetine.
5-mg dose is lower than the doses approved for psychiatric indications of paroxetine, which range from an initial dose of 10 mg to a maximum of 60 mg/day, depending on the indication.
We were quite surprised when paroxetine came out as an active compound -a result, we later determined, of what seems to be a completely new effect unrelated to its antidepressant actions and not shared by any other known antidepressant drug.