parkinsonism


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Related to parkinsonism: Parkinson's disease

parkinsonism

 [pahr´kin-sun-izm]
any disorder manifesting the symptoms of parkinson's disease or any such symptom complex occurring secondarily to another disorder, such as encephalitis, cerebral arteriosclerosis, poisoning with certain toxins, and neurosyphilis.

par·kin·son·ism

(par'kin-son-izm),
1. A neurologic syndrome usually resulting from deficiency of the neurotransmitter dopamine as the consequence of degenerative, vascular, or inflammatory changes in the basal ganglia; characterized by rhythmic muscular tremors, rigidity of movement, festination, droopy posture, and masklike facies. Synonym(s): Parkinson disease, shaking palsy, trembling palsy
2. A syndrome similar to parkinsonism. Some features seen with Parkinson disease that occur with other disorders (for example, progressive supranuclear palsy) or as a side effect of certain medications (for example, antipsychotic drugs).
[J. Parkinson]

parkinsonism

or

Parkinsonism

(pär′kĭn-sə-nĭz′əm)
n.
1. A syndrome characterized by tremor, muscular rigidity, slowness of movement, and postural and balance abnormalities, caused by Parkinson's disease or other diseases or induced by trauma, infection, or a drug. Also called Parkinson's syndrome.
2. Parkinson's disease.

par′kin·so′ni·an (-sō′nē-ən) adj.

par·kin·son·ism

(pahr'kin-sŏn-izm)
1. A neurologic syndrome usually resulting from deficiency of the neurotransmitter dopamine as the consequence of degenerative, vascular, or inflammatory changes in the basal ganglia; characterized by rhythmic muscular tremors, rigidity of movement, festination, droopy posture, and masklike facies.
Synonym(s): Parkinson disease.
2. A syndrome similar to parkinsonism appearing as an adverse effect of some antipsychotic drugs.
[J. Parkinson]

Parkinsonism

An obsolescent term for PARKINSON'S DISEASE of known causation.

Parkinsonism

A set of symptoms originally associated with Parkinson disease that can occur as side effects of neuroleptic medications. The symptoms include trembling of the fingers or hands, a shuffling gait, and tight or rigid muscles.

par·kin·son·ism

(pahr'kin-sŏn-izm)
Neurologic syndrome usually resulting from deficiency of neurotransmitter dopamine as consequence of degenerative, vascular, or inflammatory changes in basal ganglia; characterized by rhythmic muscular tremors, rigidity of movement, festination, droopy posture, and masklike facies.
Synonym(s): Parkinson disease.
[J. Parkinson]

Patient discussion about parkinsonism

Q. What to expect from a Parkinson's patient? My 70 year old father has been diagnosed with Parkinson's. What will he be like from now on, what to expect?

A. Some of the symptoms of Parkinson's disease are:
• Trembling of hands, arms, legs, jaw and face
• Stiffness of the arms, legs and trunk
• Slowness of movement
• Poor balance and coordination
The symptoms usually get worse with time and then people with the disease may have trouble walking, talking or doing simple tasks.

Q. what is the latest on parkinson?

A. the "National Institute of Neurological Disorders and Stroke" keeps an article on "what's new in Parkinson research" and they update it every now and then. i have to say that the last one is from 2005, but it has some interesting things you might wanna know...:

http://www.ninds.nih.gov/disorders/parkinsons_disease/parkinsons_research.htm

and the "National Parkinson Foundation" also keeps their readers updated and have a jornal you may find useful things in:

http://www.parkinson.org/NETCOMMUNITY/Page.aspx?pid=246&srcid=201

Q. How do you tell between temporal shaky hands and parkinson disease? My dear granpa's hands are being a bit shaky lately. I was wondering if I should worry about Parkinson's disease or is it most likely to be something else? How to tell? are there other symptoms for Parkinson's?? Any help...

A. The tremor (shaking body parts) of Parkinson disease appears during rest of the limb and disappears or weakens during active movement. Additionally, Parkinson's disease cause walking problems and slow movements.

You may read more here:
http://www.nlm.nih.gov/medlineplus/parkinsonsdisease.html

More discussions about parkinsonism
References in periodicals archive ?
In the case of parkinsonism, the lifetime risk peaked earlier than it did for dementia and stroke, and was relatively low after the age of 85 years, with no significant differences in risk between men and women.
These studies provide examples for the association of mtDNA alterations, alone or in combination with nuclear gene mutations, with parkinsonism, and point to a role of mtDNA alterations in modifying penetrance of nuclear DNA mutations.
It is debatable whether her citalopram-responsive depression was a manifestation of parkinsonism or a separate disease process.
This increase in synaptic dopamine could also be reflected by the lower levels of Parkinsonism among the smokers.
In parkinsonism, globus pallidus interna hyperactivity results in more inhibitory GABAergic input to the PPN, leading to reduced activity of the glutamatergic PPN neurons, which project to the reticulospinal neurons of brainstem and spinal cord, causing abnormal changes in locomotion and muscle tone.[sup][21] MSA has more rapid and widespread pathology than PD.
In the present study, we evaluated the difference in the status of DAT depending on Parkinsonism, cerebellar, and autonomic features and assessed whether F-18 FP-CIT PET could be useful in the treatment of Parkinsonism in MSA-C.
We believe that the cases herein described are illustrative of parkinsonism as an early manifestation of neurodegeneration induced/facilitated by chronic asymptomatic HIV infection despite adequate ART.
In particular, cognitive fluctuations, visual hallucinations and idiopathic parkinsonism have a high rate of incidence and are considered to be core symptoms of the disease.
A more difficult clinical distinction (not addressed in this study) is the patient with cognitive symptoms and Parkinsonism who may have DLB, atypical AD, or frontotemporal lobar degeneration.
Certain cerebrospinal fluid biomarkers may help differentiate Parkinson's disease from other causes of parkinsonism and also predict which patients will later develop Parkinson's-related dementia, a report shows.
(2) However, parkinsonism, as a movement disorder, is an extremely rare manifestation of NPSLE.
It covers tremors, Parkinsonism, Parkinson's disease, dystonia, chorea, myoclonus, ataxia, and tics, and medical, surgical, and nonpharmacologic approaches to treatment, including nutritional, physical, occupational, speech, and swallowing therapy.