The other 2 had parkinsonian syndrome
and were diagnosed as having CBD.
The apomorphine test in parkinsonian syndromes
[1, 3] gives a response within 15-30 minutes and may thus have a time advantage over the levodopa test.
DAT imaging was considered positive for Parkinsonian syndrome
in cases that had a reduction in [[sup.123]I][beta]-CIT uptake of 30% when compared with a healthy control database (n=93).
Whilst Parkinson's disease is the commonest cause of a parkinsonian syndrome
, there are several other degenerative and nondegenerative diseases (Table 1) that can mimic it.
As a neurologist, I was seeing several patients for evaluation of parkinsonian syndrome
, dyskinesia, or seizures.
There are several theories on the role of environmental factors in the development of IP, including the suggestion of increased vulnerability of "old" neurons to environmental toxins. One-methyl-4-phenyl-1,2,3,6-tetrahydrophridine (MPTP), a contaminant of illegally synthesized heroin, acts to induce a Parkinsonian syndrome
 Although this finding is considered specific for PKAN, it can be found in other parkinsonian syndromes
Wszolek, "Atypical parkinsonian syndromes
: a general neurologist's perspective," European Journal of Neurology, vol.
Their ensuing ceiling effects give them a low detection rate for cognitive impairment in Parkinsonian syndromes
Peng et al., "Differential diagnosis of parkinsonian syndromes
using F-18 fluorodeoxyglucose positron emission tomography," Neuroradiology, vol.
Among the side effects attributed to valproic acid, parkinsonian syndromes
and cognitive impairment were not commonly reported.
The radiolabeled dopamine transporter receptor is used with single-photon emission computed tomography imaging for potential differential diagnosis of Parkinsonian syndromes
and Dementia with Lewy Bodies.