parietal cell


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pa·ri·e·tal cell

one of the cells of the gastric glands; it lies on the basement membrane, covered by the chief cells, and secretes gastric intrinsic factor and HCl, the latter of which reaches the lumen of the gland through fine intracellular and intercellular canals (canaliculi).
Synonym(s): acid cell, oxyntic cell

parietal cell

n.
One of the large peripheral cells of the mucous membrane of the stomach that secrete hydrochloric acid.

pa·ri·e·tal cell

(pă-rī'ĕ-tăl sel)
One of the cells of the gastric mucosa; it lies on the basement membrane, covered by the chief cells, and secretes hydrochloric acid, which reaches the lumen of the gland through fine intracellular and intercellular canals (canaliculi).
Synonym(s): acid cell, oxyntic cell.

oxyntic cell

or

parietal cell

any of the glandular cells lying in pits within the wall of the vertebrate stomach. Their function is to secrete hydrochloric acid, giving the gastric fluids a pH of about 2.0.
References in periodicals archive ?
The formulation of PPIs ensures that, following absorption into the plasma, they accumulate in the gastric parietal cells. This means they do not affect other proton pumps in tissues elsewhere in the body.
To achieve the same effect all PPIs are marketed in delayed-release enteric-coated form so that they do not get activated by acid in the stomach but they dissolve in the intestine from where the drugs take a detour through general circulation and appear at the doorstep of H+/K+ ATPase pumps located on parietal cells of gastric mucosa.
PA is macrocytic anemia due to vitamin B12 deficiency as a result of deficiency of intrinsic factor because of the atrophy of gastric mucosa and thus the loss of parietal cells.9 Varying incidence rates of PA have been reported.1011
These results suggested that they did not block the [H.sub.2] receptors at gastric parietal cells or influence the intracellular mechanisms involved with histamine activity.
The vitamin then forms a complex with intrinsic factor, a specific glycoprotein that is secreted postprandially by parietal cells in the gastric lining, and moves toward the ileum to attach to receptors on the terminal ileum membrane.
Following the earlier literature and current conventions, Dahlgren and Clifford (1982) identified two characters relating to the micropylar region of the nucellus in monocotyledons: (1) presence or absence of parietal cell (sometimes called "tapetal cell," or Deckzellen) and (2) presence or absence of a multiseriate nucellar cap derived from cell divisions in the nucellar epidermis.
Esopha-geal stenosis at the cervico-thoracic junction, gastric lamina propria fibrosis, atrophic gastritis, parietal cell dropouts, and esophageal intraepithelial lymphocytosis were extremely common, whereas recurrent enteropathy and enterocolitis with striking villous atrophy, extensive apoptosis, and anaphase bridging pointing toward regenerating defect were very commonly reported in the lower GI tract.
Parietal cell antibodies among Peruvians with gastric pathology.
* PARIETAL CELL VAGOTOMY: for unresectable Gastrinomas.
Archesporium produces a parietal cell and a primary sporogenous cell.
During follow-up, all autoimmune serologic tests--including tests for anti-smooth-muscle antibodies, antimitochondrial antibodies, gastric parietal cell antibodies, rheumatoid factor, anti-Rho, anti-La, SS-A, SS-B, RNP, and antinuclear antibodies--were negative.
Histamine stimulates gastric acid secretion by direct interaction at the parietal cell [H.sub.2]-receptors that are coupled to the adenylyl cyclase system through G proteins.