parietal cell


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pa·ri·e·tal cell

one of the cells of the gastric glands; it lies on the basement membrane, covered by the chief cells, and secretes gastric intrinsic factor and HCl, the latter of which reaches the lumen of the gland through fine intracellular and intercellular canals (canaliculi).
Synonym(s): acid cell, oxyntic cell

parietal cell

n.
One of the large peripheral cells of the mucous membrane of the stomach that secrete hydrochloric acid.

pa·ri·e·tal cell

(pă-rī'ĕ-tăl sel)
One of the cells of the gastric mucosa; it lies on the basement membrane, covered by the chief cells, and secretes hydrochloric acid, which reaches the lumen of the gland through fine intracellular and intercellular canals (canaliculi).
Synonym(s): acid cell, oxyntic cell.

oxyntic cell

or

parietal cell

any of the glandular cells lying in pits within the wall of the vertebrate stomach. Their function is to secrete hydrochloric acid, giving the gastric fluids a pH of about 2.0.
References in periodicals archive ?
Recent evidence suggests that H pylori can trigger the development of autoimmune atrophic gastritis through a process of molecular mimicry in which the bacterial organisms take on the antigenic appearance of parietal cells.
Brodiaea, Dipterostemon, Dichelostemma, and Muilla (formerly Alliaceae, now Themidaceae) are also crassinucellate (Berg, 1978, 1996), whereas all members of Alliaceae lack parietal cells (Stenar, 1932).
12], the parietal cells release this protein and binds with it, hydrochloric acid, and an enzyme called pepsin.
On the other hand, duration of exposure to high plasma concentration of PPIs is longer in PMs and the proton pumps in parietal cells remain inactivated for longer period resulting in higher pH and a better therapeutic outcome (27-36).
His team stained and microscopically examined parietal cells from the brains of five trained monkeys and compared them with corresponding cells from four untrained monkeys.
B6: Required by the parietal cells in the stomach to produce hydrochloric acid.
Immunologically, the hallmark of pernicious anemia is the presence of autoantibodies to gastric parietal cells (AGPA), proton pump (H+K+ATPase), and to the cobalamin-absorbing protein, intrinsic factor.
Wilson speculated that marginal ulcers are caused by increased gastric acid production in the setting of surgically induced mucosal disruption and ischemia, and that proton pump inhibitor therapy is partially protective because it squelches acid production by parietal cells in the gastric pouch.
Autoimmune destruction of the IF-producing gastric parietal cells leads to IF deficiency and vitamin [B.
Intrinsic factor is secreted by the parietal cells of the stomach and is required for the intestinal absorption of vitamin [B.
Belmazol, used primarily for hyperacidity problems related to ulcers and gastroesophageal reflux disease, is a proton pump inhibitor which inhibits the hydrogen/potassium ATPase enzyme system at the secretory surface of gastric parietal cells.