As can be seen from the treatment course of our case, IgA paraproteinemia
plays an important role in nephropathy.
Scleromyxedema can also be associated with a paraproteinemia
, mainly immunoglobulin G-lambda type.
Hemolysis, lipemia, and paraproteinemia
can falsely increase direct bilirubin concentration.
Unlike LM, scleromyxedema is associated with sclerosis, paraproteinemia
, thyroid disease, or other systemic involvement (1).
Poorly responsive Standard therapy does not 8 to standard imply anticancer drugs, but therapy includes corticoids Hypogammaglobulinemia, monoclonal or oligoclonal paraproteinemia
, or absolute lymphocyte count do not by themselves constitute an indication for therapy.
There are many causes of distal RTA, which causes may be primary or (more commonly) secondary (due to paraproteinemia
, medullary sponge kidney, nephrocalcinosis, obstructive uropathy, or autoimmune disease, etc.) (4) In our patient, the history of subjective xerophthalmia, subjective xerostomia, and positive anti-SS-A (Ro) and anti-SS-B(La) along with the results of the 5-minute Schirmer's test together supported the clinical diagnosis of pSS (5).
Erythema elevatum diutinum may be associated with autoimmune diseases such as Celiac disease, Crohn's disease and rheumatoid arthritis, as well as hematological disorders such as myelodysplasia, multiple myeloma, immunoglobulin A paraproteinemia
, and lymphoma.
Scleromyxedema is a generalized papular eruption with systemic implications characterized by sclerosis, paraproteinemia
, and mucin deposition in the dermis.7 Clinical features primarily include waxy, firm, 2-to-4-mm, flat-topped papules or dome-shaped papules.
It is known that paraproteinemia
can interfere with this measurement, causing falsely undetectable HDL-C concentrations.
Clayer, "Skeletal angiomatosis in association with gastrointestinal angiodysplasia and paraproteinemia
: a case report," Journal of Orthopaedic Surgery, vol.
The IgG and IgM paraproteinemia
of the kappa type as well as IgA myeloma have been linked with pernicious anaemia [1-3].
The acquired causes include nutritional deficiencies of vitamin D or phosphate as well as renal tubular abnormalities due to a variety of causes such as burns, heavy metal exposure, certain medications, and paraproteinemia