Serum protein electrophoresis revealed monoclonal paraproteinemia
in high abundance marked by an intense band in the y region.
While investigating for paraproteinemia
, type of paraprotein should always be mentioned, as different flow cytometric immunophenotyping marker studies are required to be carried out.
Both neoplastic and non-neoplastic disorders are associated with monoclonal paraproteinemia
Cellular abnormalities found in patients with HIV/AIDS include dysplasia, myeloid maturation, dyserythropoiesis, erythroid hypoplasia, megakaryocytic dysplasia, changes in cellularity (normocellular or hypercellular), hypercellular), plasma cell changes, paraproteinemia
, and changes in the bone marrow matrix (1).
Grandmother Yolan Beadle, 76, suffers from a condition called paraproteinemia
, which means flu can be particularly dangerous.
Conclusions: Clinicians should proceed with caution before aggressively treating abnormal phosphorus levels in patients with known paraproteinemia
Any condition that affects the processes involved in normal urine production including renal disease, hypertension, toxemia, fever, paraproteinemia
, postural changes, stress, exposure to cold, exercise, and salicylate therapy, may lead to proteinuria.
Patients predisposed to acute renal failure include patients with any degree of pre-existing renal insufficiency, diabetes mellitus, age >65, volume depletion, sepsis, paraproteinemia
, or patients receiving known nephrotoxic drugs.
Associated with rare cases of WM is a clinical presentation of diffuse urticaria and IgM paraproteinemia
called Schnitzler syndrome.
can hinder lipoprotein clearance, thereby increasing circulating cholesterol while artifactually lowering cholesterol measurements (1).
Contrast media are potentially hazardous in patients with multiple myeloma or other paraproteinemia
Another limitation of the ESR worth emphasizing is that it may rise with conditions that are not clearly associated with inflammation, such as advancing age or the presence of serum paraproteinemia