paraprotein
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paraprotein
[par″ah-pro´tēn]a normal or abnormal plasma protein appearing in large quantities as a result of some pathologic condition, now replaced in most contexts by the term m component.
par·a·pro·tein
(par'ă-prō'tēn),1. A monoclonal immunoglobulin of blood plasma, observed electrophoretically as an intense band in γ, β, or α regions, due to an isolated increase in a single immunoglobulin type as a result of a clone of plasma cells arising from the abnormal rapid multiplication of a single cell. The finding of a paraprotein in a patient's serum indicates the presence of a proliferating clone of immunoglobulin-producing cells and may be seen in a variety of malignant, benign, or nonneoplastic diseases.
2. Synonym(s): monoclonal immunoglobulin
[para + protein, fr. G. protos, first]
M spike
A term of art referring to a zone of increased concentration of a monoclonal immunoglobulin when seen by serum electrophoresis.par·a·pro·tein
(par'ă-prō'tēn)1. A monoclonal immunoglobulin of the blood plasma, produced by a clone of plasma cells arising from the abnormal rapid multiplication of a single cell. Paraprotein in serum may be seen in various malignant, benign, or nonneoplastic diseases.
2. Synonym(s): monoclonal immunoglobulin.
[para + protein, fr. G. protos, first]
paraprotein
An abnormal plasma protein such as the MONOCLONAL immunoglobulin in MYELOMATOSIS.Paraprotein
M-protein; abnormal immunoglobulin produced in multiple myeloma.
Mentioned in: Multiple Myeloma